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Mammary analogue secretory carcinoma involving submandibular gland: Diagnostic pitfall with review of literature.
J Cancer Res Ther
July 2024
Department of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India.
Mammary analogue secretory carcinoma (MASC) is a recently defined entity among salivary gland tumors. MASC bores a striking resemblance to secretory carcinoma of breast along with the characteristics of ETV6-NTRK3 translocation. Hence, the entity was designated as MASC and was formally included in the 4th edition of World Health Organization classification of head and neck tumors in 2017.
View Article and Find Full Text PDFSATB2 expression in oral sarcomatoid (spindle cell) squamous cell carcinoma: clinicopathologic and immunophenotypic characterization of 10 cases.
Oral Surg Oral Med Oral Pathol Oral Radiol
January 2025
Division of Oral and Maxillofacial Pathology, The Ohio State University College of Dentistry, Columbus, OH, USA.
Article Synopsis
- The study investigates 10 cases of sarcomatoid squamous cell carcinoma (sSCC), a rare type of oral cancer, examining their clinicopathologic and immunophenotypic characteristics, particularly looking at SATB2 expression.
- These cases, collected from 2000 to 2023, primarily affected older adults with a male-to-female ratio of 1.5:1, most commonly occurring in the tongue, and showed a variety of tumor appearances and microscopic features.
- Results indicated that while all lesions tested positive for certain markers, SATB2 expression can vary significantly and may lead to misdiagnosis, highlighting the importance of using multiple markers for accurate identification of oral s
An assessment of "neuroendocrine differentiation" in malignant melanomas of the sinonasal and oral region.
Ann Diagn Pathol
December 2024
Osmangazi University Medical Faculty, Department of Biostatistics, 26160 Odunpazarı, Eskişehir, Turkey. Electronic address:
Article Synopsis
- Mucosal melanomas, particularly in the oral and sinonasal regions, present diagnostic challenges due to their varied characteristics and differentiation patterns, including neuroendocrine features.
- A study of 18 cases revealed that 72.2% displayed neuroendocrine differentiation, suggesting it is a common feature in these types of melanoma.
- The research highlights the importance of recognizing neuroendocrine markers (like synaptophysin, chromogranin, CD56, and INSM-1) in preventing misdiagnoses in malignant melanomas.
[Homemade CAD-CAM surgical guide for palatal mini-screw insertion for maxillary molar distalization providing anchorage. A two times original protocol].
Orthod Fr
August 2024
Université Côte d’Azur, Faculté de Chirurgie dentaire, Département d’Orthodontie, 06000 Nice, France
Introduction: Temporary Anchorage Devices have revolutionized our approach to anchorage management. However, their placement may carry risks, such as root perforation, damage to the periodontal ligament, buccal-nasal communication, etc. The aim of this article is to describe an original protocol in two times for the placement of a palatal mini-screw through guided surgery using a guide created by Computer-Aided Design and Manufacturing (CAD/CAM) followed by the transfer of placement information to the laboratory for the fabrication of a Custom Medical Device (CMD) for distalization.
View Article and Find Full Text PDFA case of larva migrans representing a pitfall in oral diagnosis.
J Oral Sci
July 2024
Stomatology Department, School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul.
Article Synopsis
- A female patient experienced itching and painful lesions in her mouth for 7 months, with symptoms including swelling and serpentine tracks on her buccal and lip mucosa.
- She was diagnosed with oral larva migrans, a parasitic infection, which resolved after treatment with ivermectin.
- At an 18-month follow-up, there were no signs of recurrence, highlighting the importance for oral health providers to consider this condition when diagnosing similar oral lesions.
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