Objective: The objective of this study was to examine whether cochlear implantation using the round window (RW) route versus cochleostomy achieves comparable electrode impedance and hearing results.
Methods: This retrospective analysis included 40 patients receiving a cochlear implant (REZ-1): 20 using the RW approach and the remaining 20 using cochleostomy. Electrode impedance and tone, vowel, consonant, disyllable and sentence perception were measured during and after the implantation.
Results: Electrode impedance did not differ significantly between the 2 groups at any time points [F(1, 38) = 1.84; p = 0.184]: 1.87, 5.16, 6.47 and 6.70 kΩ in the RW group versus 2.86, 5.33, 6.92 and 8.16 kΩ in the cochleostomy group at 0, 1, 3 and 12 months, respectively. There was no significant difference between the RW and cochleostomy groups for tone (77.50 vs. 80.50%; p = 0.472), vowel (77.70 vs. 78.65%; p = 0.760), consonant (75.50 vs. 78.25%; p = 0.443), disyllable (78.60 vs. 81.50%; p = 0.317) and sentence (50.90 vs. 52.50%; p = 0.684) perception at 12 months.
Conclusion: The RW approach is comparable to cochleostomy in electrode placement as reflected by impedance and function as reflected by tone, vowel, consonant, disyllable and sentence perception.
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http://dx.doi.org/10.1159/000490764 | DOI Listing |
ACS Appl Bio Mater
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Department of Biotechnology, School of Chemical and Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi 110062, India.
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January 2025
Advanced Materials Research Laboratory, Department of Physics, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia.
Herein, we report the biosynthesis of pure NiO and NiO nanoparticles doped with Silver (Ag@NiO NPs) 2, 4, 6, and 8 mol% from aloe vera extract by solution combustion method at 400 °C and calcined at 500 °C for 3 h. By utilizing silver-doped NiO nanoparticles synthesized with Aloe Vera latex, which not only enhances the material's properties but also promotes environmentally friendly fabrication methods. The morphological, structural elemental compositions were analysed through SEM, HRTEM, SAED, XRD and EDAX.
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January 2025
Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, Cra. 30 N° 45-03, Bogotá D.C., Colombia.
Skin cancer is one of the most common types of cancer worldwide, with exposure to UVB radiation being a significant risk factor for its development. To prevent skin cancer, continuous research efforts have focused on finding suitable photoprotective ingredients from natural sources that are also environmentally friendly. This study aimed to develop oil-in-water photoprotective nanoemulsions containing marine macroalgae extract.
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Department of Chemistry, Indian Institute of Technology Palakkad, Palakkad, Kerala 678 557, India.
Chemotherapy is a crucial cancer treatment, but its effectiveness requires precise monitoring of drug concentrations in patients. This study introduces an innovative electrochemical strip sensor design to detect and continuously monitor methotrexate (MTX), a key chemotherapeutic drug. The sensor is crafted through an eco-friendly synthesis process that produces porous reduced graphene oxide (PrGO), which is then integrated with gold nanocomposites and polypyrrole (PPy) to boost the performance of a screen-printed carbon electrode (SPCE).
View Article and Find Full Text PDFPhysiol Meas
January 2025
Chair of Measurements and Sensor Technology, Technische Universitat Chemnitz, Reichenhainerstrasse 70, Chemnitz, 09111, GERMANY.
Objective: Electrical Impedance Tomography (EIT) is a non-invasive technique used for lung imaging. A significant challenge in EIT is reconstructing images of deeper thoracic regions due to the low sensitivity of boundary voltages to internal conductivity variations. The current injection pattern is decisive as it influences the current path, boundary voltages, and their sensitivity to tissue changes.
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