The correction accuracy of a pint-sized unimorph deformable mirror (DM) is significantly influenced by the nonlinear hysteresis error of piezoelectric ceramics, especially in an open-loop state. Moreover, the control bandwidth is also reduced by the nonlinearity. In this paper, we fabricated a three-unit pint-sized unimorph DM with strain gauges integrated on the actuators as a feedback layer for the first time. An experimental platform was built and utilized to test each electrode's strain signal. Testing results show that, under quasi-static condition, the hysteresis curve of the mirror's central displacement is corrected and the hysteresis rate could be reduced from 11% to less than 2% by adopting the strain feedback signal. More specifically, the DM's initial surface, Zernike defocus, together with spherical aberration can also be corrected by this method, and the correction accuracy is improved more than 20% compared to the open-loop state. By introducing a closed-loop control the gaps of the DMs under open loop are supplied. This demonstrates that adding a strain feedback layer is promising to enhance the performance of a unimorph DM.
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http://dx.doi.org/10.1364/AO.57.006102 | DOI Listing |
Ann Surg
December 2024
Department of Urology, University of Michigan, Ann Arbor, MI.
Objective: To assess the burden of ergonomic strain and to examine factors influencing intention to use wearable technology that may improve ergonomics during surgery.
Background: Surgical ergonomic strain leads to high rates of work-related musculoskeletal disorders (MSDs) and pain, contributing to early surgeon retirement and an epidemic of burnout.
Methods: A cross-sectional survey of surgeons at a single institution was conducted using two validated instruments, the Nordic Musculoskeletal Questionnaire and Unified Theory of Acceptance and Use of Technology (UTAUT2), assessing musculoskeletal strain and facilitators of wearable sensor use, respectively.
Mol Biol Cell
December 2024
Biology Department, University of Massachusetts Amherst, Amherst, MA.
The nucleus must maintain stiffness to preserve its shape and integrity to ensure proper function. Defects in nuclear stiffness caused from chromatin and lamin perturbations produce abnormal nuclear shapes common in aging, heart disease, and cancer. Loss of nuclear shape via protrusions called blebs lead to nuclear rupture that is well-established to cause nuclear dysfunction, including DNA damage.
View Article and Find Full Text PDFSynth Syst Biotechnol
November 2024
Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
Biotin (vitamin B) is a crucial cofactor for various metabolic processes and has significant applications in pharmaceuticals, cosmetics, and animal feed. , a well-studied Gram-positive bacterium, presents a promising host for biotin production due to its Generally Recognized as Safe (GRAS) status, robust genetic tractability, and capacity for metabolite secretion. This study focuses on the metabolic engineering of .
View Article and Find Full Text PDFPlatelets
December 2024
Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Invasive non-typhoidal infections are responsible for >75 000 deaths/year and >500 000 cases/year globally. Seventy-five percent of these cases occur in Sub-Saharan Africa, an increasing number of which are from multi-drug resistant strains. Interactions between bacteria and platelets can lead to thrombus formation, which can be beneficial for control of infection (immunothrombosis), or harmful through uncontrolled inflammation and organ damage (thromboinflammation).
View Article and Find Full Text PDFBioinspir Biomim
December 2024
College of Information Science and Engineering, Northeastern University, Shenyang, Liaoning 110819, People's Republic of China.
The field of pneumatic soft robotics is on the rise. However, most pneumatic soft robots still heavily rely on rigid valves and conventional electronics for control, which detracts from their natural flexibility and adaptability. Efforts have focused on substituting electronic controllers with pneumatic counterparts to address this limitation.
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