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Inter-Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five-Nations Survey Study.
United European Gastroenterol J
January 2025
Sheba Medical Center, Institute of Gastroenterology, Ramat-Gan, Israel.
Background: The Montreal classification has been widely used in Crohn's disease since 2005 to categorize patients by the age of onset (A), disease location (L), behavior (B), and upper gastrointestinal tract and perianal involvement. With evolving management paradigms in Crohn's disease, we aimed to assess the performance of gastroenterologists in applying the Montreal classification.
Methods: An online survey was conducted among participants at an international educational conference on inflammatory bowel diseases.
AI contextual information shapes moral and aesthetic judgments of AI-generated visual art.
Cognition
January 2025
Social Brain Sciences Group, Department of Humanities, Social and Political Sciences, ETH Zurich, Zurich, Switzerland. Electronic address:
Throughout history, art creation has been regarded as a uniquely human means to express original ideas, emotions, and experiences. However, as Generative Artificial Intelligence reshapes visual, aesthetic, legal, and economic culture, critical questions arise about the moral and aesthetic implications of AI-generated art. Despite the growing use of AI tools in art, the moral impact of AI involvement in the art creation process remains underexplored.
View Article and Find Full Text PDFNeural Variability and Cognitive Control in Individuals With Opioid Use Disorder.
JAMA Netw Open
January 2025
Interdepartmental Neuroscience Program, Yale University, New Haven, Connecticut.
Importance: Opioid use disorder (OUD) impacts millions of people worldwide. Prior studies investigating its underpinning neural mechanisms have not often considered how brain signals evolve over time, so it remains unclear whether brain dynamics are altered in OUD and have subsequent behavioral implications.
Objective: To characterize brain dynamic alterations and their association with cognitive control in individuals with OUD.
Rethinking Gender: Beyond the Binary and into the Unknown.
Integr Psychol Behav Sci
January 2025
Bennett University, Greater Noida, India.
Our present and evolved understanding has challenged the previously synonymous use of the terms 'sex' and 'gender'. We have moved beyond the binary categorization towards proliferation of gender identities. Thus, raising questions whether certain identities are traits or gender identities.
View Article and Find Full Text PDFThe Landmark Series: The Future of Pancreatic Cancer Clinical Trials.
Ann Surg Oncol
January 2025
Division of Surgery, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Pancreatic cancer has a poor prognosis despite ongoing advances in systemic and multimodal therapies. This review analyzes recent progress and future directions in pancreatic cancer clinical trials, emphasizing the evolution from traditional approaches to a more personalized and biologically-driven treatment paradigm. While improvements in overall survival have been achieved through perioperative therapies, gaps remain in our understanding of optimal treatment strategies.
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