We introduce an Interaction- and Trade-off-based Eco-Evolutionary Model (ITEEM), in which species are competing in a well-mixed system, and their evolution in interaction trait space is subject to a life-history trade-off between replication rate and competitive ability. We demonstrate that the shape of the trade-off has a fundamental impact on eco-evolutionary dynamics, as it imposes four phases of diversity, including a sharp phase transition. Despite its minimalism, ITEEM produces a remarkable range of patterns of eco-evolutionary dynamics that are observed in experimental and natural systems. Most notably we find self-organization towards structured communities with high and sustained diversity, in which competing species form interaction cycles similar to rock-paper-scissors games.
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http://dx.doi.org/10.7554/eLife.36273 | DOI Listing |
Ecology
January 2025
Bodega Marine Laboratory, University of California Davis, Bodega Bay, California, USA.
A growing body of theoretical studies and laboratory experiments has focused attention on reciprocal feedbacks between ecological and evolutionary processes. However, uncertainty remains about whether such eco-evolutionary feedbacks have an important or negligible influence on natural communities. Thus, recent discussions call for field experiments that explore whether selection on phenotypic variation within populations leads to contemporaneous effects on community dynamics.
View Article and Find Full Text PDFMath Biosci Eng
December 2024
Aix Marseille Univ, Université de Toulon, CNRS, IRD, MIO, Marseille, France.
Environmental changes are a growing concern, as they exert pressures on ecosystems. In some cases, such changes lead to shifts in ecosystem structure. However, species can adapt to changes through evolution, and it is unclear how evolution interacts with regime shifts, which restricts ecosystem management strategies.
View Article and Find Full Text PDFWhile the genetic paradigm of cancer etiology has proven powerful, it remains incomplete as evidenced by the widening spectrum of non-cancer cell-autonomous "hallmarks" of cancer. Studies have demonstrated the commonplace presence of high oncogenic mutational burdens in homeostatically-stable epithelia. Hence, the presence of driver mutations alone does not result in cancer.
View Article and Find Full Text PDFFront Netw Physiol
December 2024
Faculty of Medicine, Hadassah Medical Center, Hebrew University, Jerusalem, Israel.
The Constrained Disorder Principle (CDP) defines all systems in nature by their degree of inherent variability. Per the CDP, the intrinsic variability is mandatory for their proper function and is dynamically changed based on pressures. The CDP defines the boundaries of inherent variability as a mechanism for continuous adaptation to internal and external perturbations, enabling survival and function under dynamic conditions.
View Article and Find Full Text PDFNat Commun
December 2024
Centre for Ecological and Evolutionary Synthesis, Department of Biosciences, University of Oslo, Oslo, Norway.
Short tandem repeats (STRs) have emerged as important and hypermutable sites where genetic variation correlates with gene expression in plant and animal systems. Recently, it has been shown that a broad range of transcription factors (TFs) are affected by STRs near or in the DNA target binding site. Despite this, the distribution of STR motif repetitiveness in eukaryote genomes is still largely unknown.
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