Neuronal endosomes to lysosomes: A journey to the soma.

J Cell Biol

Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Published: September 2018

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Article Abstract

How are lysosomal degradation pathways spatially organized in the complex landscape of a neuron? Cheng et al. (2018. https://doi.org/10.1083/jcb.201711083) and Yap et al. (2018. https://doi.org/10.1083/jcb.201711039) characterize the distribution and function of endolysosomal organelles in neurons, providing insights into compartment-specific mechanisms regulating the neuronal proteome.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123003PMC
http://dx.doi.org/10.1083/jcb.201806139DOI Listing

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