Introduction: In 2016, the World Health Organization implemented a Global Strategy to eliminate viral hepatitis. For Hepatitis C, the goals of this Strategy include increased harm reduction coverage, improved safety of medical procedures and an increase the percentage of people diagnosed and treated.
Objective: This article aims are evaluating the epidemiological situation of HCV infections in Poland in 2016 in reference to the data from previous years.
Material And Methods: Analysis of epidemiological situation of hepatitis C in Poland in 2016 was carried out on case-based data collected through routine surveillance system. Data on hepatitis C mortality from the Demographic Surveys and Labour Market Department of the Central Statistical Office were also included.
Results: In 2016, a total of 4,261 cases were reported. Diagnosis rate was 11.09 per 100,000, on the similar level as in 2015 (1% decrease), but in comparison to the median for the years 2010-2014 it increased by 88%. The most common possible route of HCV infection were medical procedures accounting for 69.8% of all cases and for 58.2% of acute hepatitis C virus infection cases. In 2016, 224 deaths due to hepatitis C were registered. In 2016, a hepatitis C outbreak was reported in małopolskie voivodeship (11 patients of the Hemato-oncolology Department, 129 people exposed).
Conclusions: The increase of HCV diagnosis rate, which has been reported for last three years, is probably a consequence of improved the surveillance, including mandatory reporting of positive laboratory results, but also increased availability of HCV laboratory screening. Medical exposures are still an important route of transmission of HCV in Poland.
Download full-text PDF |
Source |
---|
Heliyon
January 2025
BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre Nedlands and Centre for Medical Research, The University of Western Australia, Perth, Australia.
Breast-conserving surgery accompanied by adjuvant radiotherapy is the standard of care for patients with early-stage breast cancer. However, re-excision is reported in 20-30 % of cases, largely because of close or involved tumor margins in the specimen. Several intraoperative tumor margin assessment techniques have been proposed to overcome this issue, however, none have been widely adopted.
View Article and Find Full Text PDFPharmacoeconomics
January 2025
Belgian Health Care Knowledge Centre, Brussels, Belgium.
Background: Forecasting future public pharmaceutical expenditure is a challenge for healthcare payers, particularly owing to the unpredictability of new market introductions and their economic impact. No best-practice forecasting methods have been established so far. The literature distinguishes between the top-down approach, based on historical trends, and the bottom-up approach, using a combination of historical and horizon scanning data.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Department of Electroradiology, Poznan University of Medical Sciences, Garbary 15, 61-866 Poznan, Poland.
The vast majority of breast cancer patients require radiotherapy but some of them will develop local recurrences and potentially metastases in the future. Recent data show that exosomal cargo is essential in these processes. Thus, we investigated the influence of ionising radiation on exosome properties and their ability to modify the sensitivity and biology of non-irradiated cells.
View Article and Find Full Text PDFJ Appl Genet
January 2025
Department of Neurogenetics and Functional Genomics, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawińskiego 5, 02-106, Warsaw, Poland.
Gilles de la Tourette syndrome (GTS) and other tic disorders (TDs) have a substantial genetic component with their heritability estimated at between 60 and 80%. Here we propose an oligogenic risk score of TDs using whole-genome sequencing (WGS) data from a group of Polish GTS patients, their families, and control samples (n = 278). In this study, we first reviewed the literature to obtain a preliminary list of 84 GTS/TD candidate genes.
View Article and Find Full Text PDFBMC Geriatr
January 2025
Department of Emergency Medical Service, Faculty of Nursing and Midwifery, Wroclaw Medical University, Wroclaw, 51-618, Poland.
Background: Hypertension is a common condition among the elderly and is frequently accompanied by frailty syndrome (FS). The coexistence of hypertension and FS poses significant challenges in patient management and negatively impacts the quality of life (QoL). This study aimed to analyze the relationship between FS and QoL in elderly patients with suspected hypertension.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!