Purpose: This study's purpose was to optimize the efficiency of and to design a scalable research scheduling team to meet the growing demands of an academic cancer center with increasing clinical trial accruals.
Methods: The Plan, Do, Study, Act improvement methodology was deployed to increase the efficiency of research scheduling, to reduce non-value-added (NVA) activities, and to reduce cycle time to meet takt time. In the Plan phase, voice-of-the-customer interviews were conducted. In the Do phase, the baseline workflow was mapped and billing data were analyzed. In the Study phase, cycle time, takt time, and capacity analysis metrics were calculated at baseline. In the Act phase, interventions were implemented to increase efficiency by reducing NVA activities and increasing value-added activities, and metrics were reassessed after intervention.
Results: An 8% increase in appointment requests was noted from baseline to after intervention, and the cycle time for appointment scheduling decreased by 11%, demonstrating increased efficiency. Process steps decreased from 15 to 10, eliminating NVA activities and rework and waiting, two types of waste.
Conclusion: Although efficiency increased, the number of total appointments scheduled weekly increased by 4%, resulting in a reduced takt time, or a shorter time to schedule each appointment to meet demand. A capacity analysis demonstrated that even after interventions, an additional 0.5 full-time employee is required to reduce cycle time to equal takt time. Capacity analysis creates a scalable framework for the scheduling team and facilitates movement from reactive to proactive staffing, which can be applied throughout the research enterprise.
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http://dx.doi.org/10.1200/JOP.18.00071 | DOI Listing |
J Biol Rhythms
January 2025
Department of Physics and i3n, University of Aveiro, Aveiro, Portugal.
The role of the hierarchical organization of the suprachiasmatic nucleus (SCN) in its functioning, jet lag, and the light treatment of jet lag remains poorly understood. Using the core-shell model, we mimic collective behavior of the core and shell populations of the SCN oscillators in transient states after rapid traveling east and west. The existence of a special region of slow dynamical states of the SCN oscillators can explain phenomena such as the east-west asymmetry of jet lag, instances when entrainment to an advance is via delay shifts, and the dynamics of jet lag recovery time.
View Article and Find Full Text PDFJMIR Med Educ
January 2025
Centre for Digital Transformation of Health, University of Melbourne, Carlton, Australia.
Background: Learning health systems (LHS) have the potential to use health data in real time through rapid and continuous cycles of data interrogation, implementing insights to practice, feedback, and practice change. However, there is a lack of an appropriately skilled interprofessional informatics workforce that can leverage knowledge to design innovative solutions. Therefore, there is a need to develop tailored professional development training in digital health, to foster skilled interprofessional learning communities in the health care workforce in Australia.
View Article and Find Full Text PDFFront Immunol
January 2025
Faculty of Life and Biotechnology, Kunming University of Science and Technology, Kunming, China.
Background: Dysbiosis of the lung microbiome can contribute to the initiation and progression of lung cancer. Synchronous multiple primary lung cancer (sMPLC) is an increasingly recognized subtype of lung cancer characterized by high morbidity, difficulties in early detection, poor prognosis, and substantial clinical challenges. However, the relationship between sMPLC pathogenesis and changes in the lung microbiome remains unclear.
View Article and Find Full Text PDFIran J Basic Med Sci
January 2025
Department of Physiology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey.
Objectives: This study aimed to investigate the potential effects of different doses of essential oil (Lavender EO) administered by inhalation on sleep latency and neuromodulators regulating the sleep/wake cycle in rats with total sleep deprivation (TSD).
Materials And Methods: Forty-eight male Sprague-Dawley rats were divided into five groups: Control, Alprazolam (ALP, 0.25 mg/kg given intraperitoneally), L1 (Lavender EO, 0.
Gates Open Res
January 2025
University of Virginia, Charlottesville, Virginia, USA.
Background: The TaqMan Array Card (TAC) is an arrayed, high-throughput qPCR platform that can simultaneously detect multiple targets in a single reaction. However, the manual post-run analysis of TAC data is time consuming and subject to interpretation. We sought to automate the post-run analysis of TAC data using machine learning models.
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