We present a revised method for estimating equivalence scales. Such scales are used to adjust household welfare to account for the size of the household, and are used extensively in the application of the World Health Organization's (WHO) methodology for the evaluation of catastrophic health payments. Applications of the WHO method are underpinned by early estimates that do not control for household income, and, therefore, are likely to overstate equivalence. Thus, in addition to revising the method, we update the scale estimates for one country, South Africa, using more recent data. South Africa is considered, because the end of Apartheid has led to extensive social and economic changes that have influenced household structure and, presumably, equivalence. We also present information on the possible degree to which earlier estimates are overstated, as well as the effect that has on other components of the WHO method, especially the determinants of out-of-pocket expenditures and catastrophic health payments. We find that, in the worst case, initial estimates could be overstated by as much 46%, leading to the understatement of poverty lines by as much as 17%. Despite these large differences, the average incidence of catastrophe in health expenditure was largely unaffected. Instead, differences in scales affect conclusions related to the determinants of out-of-pocket payments and catastrophic health expenditures, as well as the distribution of catastrophe across household size. Given that South Africa has low levels of catastrophic health expenditure, the effect could be even larger in other countries, and, therefore, we recommend that researchers consider a range of scales, when examining catastrophic health expenditures.
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http://dx.doi.org/10.1093/heapol/czy072 | DOI Listing |
BMC Oral Health
January 2025
Department of Fixed Prosthodontics, Faculty of Dental Medicine, Al-Azhar University, Cairo, 11651, Egypt.
Purpose: The current study aimed to compare modified Polyether-ether-ketone's fracture resistance and failure mode versus lithium disilicate glass-ceramic endocrowns.
Materials And Methods: A total of 16 butt-joint endocrown specimens on mandibular second molar teeth were fabricated and divided into two equivalent groups; Pressable modified Polyether-ether-ketone (PEEK) (BioHPP) and Pressable lithium disilicate glass ceramic (IPS e.max Press).
Proc Natl Acad Sci U S A
January 2025
Département de Biologie, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.
To achieve replicative immortality, cancer cells must activate telomere maintenance mechanisms. In 10 to 15% of cancers, this is enabled by recombination-based alternative lengthening of telomeres pathways (ALT). ALT cells display several hallmarks including heterogeneous telomere length, extrachromosomal telomeric repeats, and ALT-associated PML bodies.
View Article and Find Full Text PDFSensors (Basel)
December 2024
School of Mechatronic Engineering, Xi'an Technology University, No.2 Xuefuzhonglu Road, Weiyang District, Xi'an 710021, China.
Aero-engines, particularly turbofan engines, are highly complex systems that play a critical role in the aviation industry. As core components of modern aircraft, they provide the thrust necessary for flight and are essential for safe and efficient operations. However, the complexity and interconnected nature of these engines also make them vulnerable to failures and, in the context of intelligent systems, potential cyber-attacks.
View Article and Find Full Text PDFClin Transl Med
January 2025
Department of Urology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Background: Chromosomal instability (CIN), a hallmark of cancer, is commonly linked to poor prognosis in high-grade prostate cancer (PCa). Paradoxically, excessively high levels of CIN may impair cancer cell viability. Consequently, understanding how tumours adapt to CIN is critical for identifying novel therapeutic targets.
View Article and Find Full Text PDFSci Rep
January 2025
Oeschger Centre for Climate Change Research (OCCR), University of Bern, Bern, Switzerland.
The impacts of climate change on human health are often underestimated or perceived to be in a distant future. Here, we present the projected impacts of climate change in the context of COVID-19, a recent human health catastrophe. We compared projected heat mortality with COVID-19 deaths in 38 cities worldwide and found that in half of these cities, heat-related deaths could exceed annual COVID-19 deaths in less than ten years (at + 3.
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