ERP indices of performance monitoring and feedback processing in psychosis: A meta-analysis.

Int J Psychophysiol

VA Greater Los Angeles Healthcare System, United States of America; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, United States of America.

Published: October 2018

AI Article Synopsis

  • Individuals with psychotic disorders showed a significant reduction in early error-related negativity (ERN), indicating substantial impairments in performance monitoring compared to healthy controls.
  • Those at heightened risk for psychotic disorders also displayed a moderate reduction in ERN, suggesting some vulnerability in this group as well.
  • Later performance monitoring (Pe) and basic feedback processing (FN) did not show significant differences between those with psychosis and controls, indicating these aspects may remain intact.

Article Abstract

Background: Although individuals with, or at risk for, psychotic disorders often show difficulties with performance monitoring and feedback processing, findings from studies using event-related potentials (ERPs) to index these processes are not consistent. This meta-analytic review focused on studies of two different indexes of performance monitoring, the early error-related negativity (ERN; n = 25) and the later error positivity (Pe; n = 17), and one index of feedback processing, the feedback negativity (FN; n = 6).

Methods: We evaluated whether individuals (1) with psychotic disorders, or (2) at heightened risk for these disorders differ from healthy controls in available studies of the ERN, Pe, and FN.

Results: There was a significant, large ERN reduction in those with psychosis (g = -0.96) compared to controls, and a significant, moderate ERN reduction in those at-risk (g = -0.48). In contrast, there were uniformly non-significant, small between-group differences for Pe and FN (gs ≤ |0.16|).

Conclusions: The results reveal a differential pattern of impairment in psychosis. Early performance monitoring (ERN) impairments are substantial among those with psychotic disorders in general and may be a useful vulnerability indicator for these disorders. However, later performance monitoring (Pe) and basic feedback processing (FN) appear to be relatively spared in psychosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157731PMC
http://dx.doi.org/10.1016/j.ijpsycho.2018.08.004DOI Listing

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