AI Article Synopsis
- There are previously noted MRI abnormalities in hemiplegic migraine, mainly focused on changes in cortical thickness and blood flow patterns.
- A new case study presents the first instance of diffuse cortical enhancement in a patient with sporadic hemiplegic migraine, linking it to neuronal damage similar to ischemic lesions.
- The findings suggest that the presence of cortical contrast enhancement on MRI may indicate the severity of a migraine attack and could predict potential neuronal loss.
Article Abstract
Background: Magnetic resonance imaging abnormalities in hemiplegic migraine have been described previously but were limited to a cortical thickening and biphasic alternation of hypoperfusion and hyperperfusion. Our report reveals possible blood-brain barrier disruption during migraine.
Case: We present the first demonstrated case of regressive diffuse hemispheric cortical enhancement in sporadic hemiplegic migraine, with histological correlation revealing neuronal lesions similar to ischemic lesions. This is probably due to the severity of the attack as indicated by the left hemiplegia and transient altered consciousness in our 43-year-old male patient.
Conclusion: Cortical contrast enhancement on 3D T1 images may suggest migraine severity and be predictive of neuronal loss.
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| http://dx.doi.org/10.1177/0333102418794481 | DOI Listing |
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