How to reduce unwarranted variation in the NHS was the focus of debate among experts brought together for HSJ's latest roundtable, as Alison Moore reports.
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Parenthood, gender, and turning points to crime for young people in Latin America.
Adv Life Course Res
January 2025
Department of Political Science and Public Law, Autonomous University of Barcelona, Cerdanyola del Vallès, Bellaterra 08193, Spain.
In very different societal contexts, parenthood has been identified as a critical turning point in life course trajectories. In this qualitative study, we explore parenthood as a turning point for 40 young women and 40 young men in prisons across Latin America. We study the impact of parenthood on criminal trajectories, identify gender differences, and analyze the different mechanisms at work.
View Article and Find Full Text PDFMapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection.
NIHR Open Res
January 2025
Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, England, L69 7BE, UK.
Background: PROTECT ( Platform Randomised evaluation of clinical Outcomes using novel TEChnologies to optimise antimicrobial Therapy) has brought together a team of researchers to design a platform trial to rapidly evaluate and adopt into care multiple diagnostic technologies, bringing immediate benefit to patients. Rapid diagnostic tests will be used to identify patients at risk of deterioration from severe infection, before they become critically unwell. The platform will assess their comparative clinical effectiveness and cost-effectiveness relative to current standard of care.
View Article and Find Full Text PDFEvaluating the Cost-Effectiveness of Antenatal Screening for Major Structural Anomalies During the First Trimester of Pregnancy: A Decision Model.
BJOG
January 2025
National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Objective: To assess the cost-effectiveness of modifying current antenatal screening by adding first trimester structural anomaly screening to standard of care second trimester anomaly screening.
Design: Health economic decision model.
Setting: National Health Service (NHS) in England and Wales.
Precision in Stroke Care: A Novel Model for Predicting Functional Independence in Urgent Carotid Intervention Patients.
J Am Coll Surg
January 2025
- The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA.
Background: Stroke requires timely intervention, with carotid endarterectomy (CEA) and carotid artery stenting (CAS) increasingly used in select acute carotid-related stroke patients. We aimed to build a model to predict neurologic functional independence (modified Rankin scale, mRS ≤ 2) in this high-risk group.
Study Design: We analyzed data from 302 stroke patients undergoing urgent CEA or CAS between 2015 and 2023 at a tertiary Comprehensive Stroke Center.
Background: Accurate estimates of incremental cost (IC) attributable to antimicrobial resistance (AMR) provide information of immense public health importance to the policy makers. Here, we present the IC from patient perspective for treating antimicrobial-resistant pathogens in India.
Methods: This cohort study was conducted in eight hospitals including government (GH), private (PH) and trust hospitals (TH), considering their ownership, geographical location and categories of cities.
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