[Optimization of Stabilizing Agent of Camptothecin Extraction from Nothapodytes pittosporoides Roots].

Objective: To optimize the stabilizing agent of camptothecin extraction from Nothapodytes pittosporoides roots.

Methods: The single factor experiment had been conducted to study the impact on the yield of camptothecin with different kinds of stabilizer, stabilizer concentration and temperature.

Results: The results showed that with 0. 5% ferrous sulfate at 80 ℃,the best concentration of camptothecin extraction from Nothapodytes pittosporoides roots was got, and the yield of camptothecin after concentration reached to 94. 58%.

Conclusion: This process method is efficient and simple, which can be used to solve camptothecin reduction when the extract is concentrated, and the method is benefit for the industrialization of camptothecin extraction.