AI Article Synopsis
- - The study assessed the toxic effects of outdoor particulate matter (PM) collected in Beijing during the Spring Festival, focusing on how different concentrations affected nematodes' locomotion and intestinal reactive oxygen species (ROS) production.
- - Findings revealed a significant induction of genes related to metallothioneins in the intestine following PM exposure, suggesting a genetic basis for the toxicity.
- - A signaling pathway involving genes DAF-2, DAF-16, and others was identified, providing insight into how outdoor PM toxicity affects nematodes, which could imply risks for other environmental organisms during this time.
Article Abstract
In this study, we performed the toxicological assessment of outdoor PM collected from Beijing during Spring Festival using the assay system of . Acute exposure to outdoor PM at a concentration of 10 mg L and prolonged exposure to outdoor PM at concentrations of 0.1-10 mg L decreased locomotion behavior and caused significant induction of intestinal ROS production. Meanwhile, outdoor PM exposure induced significant expression of gene ( and ) encoded metallothioneins in the intestine. Mutation of the or gene resulted in a susceptible property of nematodes to outdoor PM toxicity. Genetic assays suggested that and genes acted downstream of the gene encoding a FOXO transcriptional factor and gene encoding an insulin receptor in the insulin signaling pathway to regulate outdoor PM toxicity. DAF-2 further acted upstream of DAF-16 and suppressed the function of DAF-16 to regulate outdoor PM toxicity. Therefore, we identified a signaling cascade of DAF-2-DAF-16-MTL-1/2 in the control of outdoor PM toxicity in nematodes. Our study provides an important molecular basis for the potential toxicity of outdoor PM during Spring Festival in Beijing in nematodes. Especially, our study will highlight the potential adverse effects of outdoor PM during Spring Festival on environmental organisms.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060693 | PMC |
| http://dx.doi.org/10.1039/c6tx00022c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Increasing Contribution of Chlorine Chemistry to Wintertime Ozone Formation Promoted by Enhanced Nitrogen Chemistry.
Environ Sci Technol
December 2024
Center for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China.
Article Synopsis
- - Chlorine radicals play a crucial role in atmospheric oxidation and pollutant behavior, but their interaction with nitrogen chemistry, specifically related to nitric oxide (NO), is not well understood.
- - This research provides evidence that increased levels of NO lead to daytime breakdown of nitrate and nighttime reactions between NO molecules, resulting in higher concentrations of chlorine-containing compounds after the Chinese Spring Festival.
- - The study emphasizes that the increase in nitrogen chemistry from NO significantly boosts chlorine reactions, ultimately enhancing the levels of ozone and the overall oxidative power of the atmosphere during winter days.
Forming national identity with televised cultural rituals: a critical discourse analysis of China's program.
Front Psychol
November 2024
School of Journalism and Information Communication, Huazhong University of Science and Technology, Wuhan, China.
Studies on media and national identity emphasize the need for a comprehensive and culturally sensitive approach to understanding the complex relationship between media and identity. This study used critical discourse analysis to examine the depiction of cultural rituals in the program and its role in forming and reinforcing national identity in China. The program, broadcast on China Central Television, showcases three traditional Chinese cultural rituals: ancestor worship, agricultural rites, and spring outings.
View Article and Find Full Text PDFHealth risks of environmentally persistent free radicals in atmospheric particulate matter during the spring festival travel season in Tainan, Taiwan.
Environ Sci Pollut Res Int
November 2024
Department of Marine Environment and Engineering, National Sun Yat-Sen University, Kaohsiung, 804, Taiwan.
Environmentally persistent free radicals (EPFRs) and polycyclic aromatic hydrocarbons (PAHs) are persistent pollutants in atmospheric particulate matter that are detrimental to human health. This study collected atmospheric particulate matter during and after the spring festival travel season in Tainan, Taiwan, from various locations and analyzed the carbon composition and PAH isomeric ratios to identify the sources. In this study, EPFR concentrations were measured using electron paramagnetic resonance spectroscopy, with the highest concentration found to be 3.
View Article and Find Full Text PDFPredicting influenza in China from October 1, 2023, to February 5, 2024: A transmission dynamics model based on population migration.
Infect Dis Model
March 2025
State Key Laboratory of Vaccines for Infectious Diseases, XiangAn Biomedicine Laboratory, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, China.
Introduction: Since November 2023, influenza has ranked first in reported cases of infectious diseases in China, with the outbreak in both northern and southern provinces exceeding the levels observed during the same period in 2022. This poses a serious health risk to the population. Therefore, short to medium-term influenza predictions are beneficial for epidemic assessment and can reduce the disease burden.
View Article and Find Full Text PDFAnalysis of Pollution Characteristics and Contributions of Firework Burnings in Nanchang during the Spring Festival.
ACS Omega
September 2024
College of Marine Resources & Environment, Hebei Normal University of Science & Technology, Hebei Key Laboratory of Ocean Dynamics, Resources and Environments, Qinhuangdao Key Laboratory of Marine Habitat and Resources, Qinhuangdao 066004, China.
This study investigates the impact of fireworks on air quality during the Spring Festival in Nanchang City, utilizing high-resolution monitoring data from February 7th to 15th, 2021. Significant variations in K concentrations were observed, indicating severe air quality impacts. During the most intense discharge event A, K concentrations were 20.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!