Pro-guest and acyclic cucurbit[n]uril conjugated polymers for the controlled release of anti-tumor drugs.

Chem Commun (Camb)

Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.

Published: August 2018

We report "pro-guest" and acyclic cucurbit[n]uril conjugated polymers as supramolecular drug delivery systems (DDSs). These supramolecular DDSs could encapsulate anti-tumor drugs. Under acidic conditions, an acid-labile "pro-guest" degraded to become a "competing guest", which displaced and released the encapsulated drug at a tunable rate.

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Source
http://dx.doi.org/10.1039/c8cc05552aDOI Listing

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