Objectives: The () is an intracellular opportunistic protozoan parasite that infects approximately one-third of the human population worldwide. Honey has long been used for treatment of many diseases in folk medicine. Honey has exhibited significant anthelmintic, nematicidal and anti-protozoal activities.This study was conducted to investigate the immunological patterns in rats infected with who were treated orally with supplemented 15% honey (Saudi Arabia) for a period of 28 days.
Methods: Immunoglobulin M, immunoglobulin G, and cytokines were detected by using enzyme-linked immunosorbent assays (ELISAs). In addition, the mortality and the morbidity rates were assessed.
Results: Oral administration of honey as a natural food additive was experimentally shown to increase the antibody titer; furthermore, compared with the rats in the control group, the levels of the sera cytokines (IFN-, IL-1 and IL-6) were consistently higher at day 7 post-infection in the infected rats treated with oral supplements of honey.
Conclusion: Orally administered supplements of honey increased both the antibody titer and the cytokines (IFN-, IL-1 and IL-6) levels in rats infected with .
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| http://dx.doi.org/10.3831/KPI.2017.20.015 | DOI Listing |
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