Child Neurology: An infant with episodic facial flushing: A rare case and review of congenital harlequin syndrome.

Neurology

From the Departments of Neurology (J.H.K.), Child Neurology (M.S.Z., K.-G.E.W.), and Pediatrics (M.S.Z., K.-G.E.W.), Duke University Medical Center, Durham, NC.

Published: August 2018

Congenital harlequin syndrome is rare dysautonomia of the face most often reported in adults and rarely in infants and children. It is a diagnosis of exclusion and a seemingly benign condition. We report a case of a 6-month-old girl with episodic unilateral and bilateral facial flushing provoked upon awakening and resolved with sleeping with associated autonomic features consistent with harlequin syndrome. This is followed by a review of cases identified regarding this condition in infants and children.

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Source
http://dx.doi.org/10.1212/WNL.0000000000005949DOI Listing

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