The [F]Fluorocholine ([F]FCH) tracer for PET imaging has been proven to be effective for several malignances. However, there are only a few studies related to its breast tumor applicability and they are still limited. The aim of this study was investigate the efficacy of [F]FCH/PET compared to [F]FDG/PET in a murine 4T1 mammary carcinoma model treated and nontreated. [F]FCH/PET showed its applicability for primary tumor and lung metastasis detection and their use for response monitoring of breast cancer therapeutics at earlier stages.

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http://dx.doi.org/10.1016/j.apradiso.2018.07.032DOI Listing

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