AI Article Synopsis
- Previous studies linked acute stress and elevated glucocorticoids to increased anxiety and changes in the dendritic structure of the basolateral amygdala in rats.
- This research shows that environmental enrichment can prevent heightened anxiety levels that emerge after stress while not inhibiting the changes to dendritic branches or the increase in stress hormone levels.
- The findings suggest that environmental factors, like enrichment, may help mitigate anxiety effects from stress without affecting the underlying physiological changes.
Article Abstract
Previous studies showed that acute restraint stress or transient elevation of glucocorticoid (GC) stress hormones produces emergent changes in both anxiety behavior and dendritic branches in the basolateral amygdala complex (BLA) of rats. In this work, we demonstrate that exposure to environmental enrichment (EE) prevented stress-induced increases in anxiety (emerging 10 days post-stress) in adult rats without blocking stress-induced dendritic branch remodeling in the BLA nor stress-induced enhancement of GC serum levels.
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| http://dx.doi.org/10.1016/j.psyneuen.2018.07.031 | DOI Listing |
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