AI Article Synopsis
- The study aimed to assess visual improvement in patients with branch retinal vein occlusion (BRVO) and macular edema following conservative treatment with aspirin and kallidinogenase.
- A total of 33 patients were analyzed, and results showed a significant difference in visual acuity improvement and central subfield thickness (CST) changes between those who improved more than 0.3 on the logMAR scale and those who didn't, particularly after one month of treatment.
- A CST reduction of over 30 μm after one month was identified as a key predictor of better visual acuity after three months, suggesting its potential as a reliable index for monitoring treatment efficacy.
Article Abstract
Purpose: To identify indices of visual improvement after conservative treatment for branch retinal vein occlusion (BRVO) with macular edema. Methods: We retrospectively reviewed the charts of 33 eyes of 33 patients with BRVO with macular edema. Inclusion criteria were 1) onset within 4 months, 2) decimal visual acuity of 0.05 to 0.5, and 3) minimum central subfield thickness (CST) of 250 μm. After 3 months of treatment with oral aspirin and kallidinogenase, the patients were divided into two groups: those with logarithmic minimum angle of resolution (logMAR) visual improvement of 0.3 or more (14 eyes) and less than 0.3 (19 eyes). We then compared systemic and ocular findings in the groups. Results: The groups differed significantly in logMAR improvement after 1 month (p<0.01) and in CST change after 1 month (p<0.05). Multiple logistic regression analysis showed that CST change after 1 month was a significant index of visual improvement (p<0.05). The cutoff value for visual improvement was -30 μm (sensitivity: 78.6, specificity: 68.4, positive predictive value: 64.7, negative predictive value: 81.3). Conclusion: A decrease in CST of more than 30 μm 1 month after conservative treatment indicates that visual acuity is likely to be improved after 3 months.
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