This study aimed to characterize metal contaminant concentrations and assess temporal and spatial variability in the main drinking water sources of Cap-Haïtien, Haiti. Water sources from five communities were sampled in two seasons, June (2014) and October (2014), and analysed for a suite of metals. A geographic information system was used to examine the spatial distribution of sampling points. Metal concentrations were below the US Environmental Protection Agency (USEPA) primary drinking water standards. Mean manganese concentrations were comparatively higher in wells (254.5 µg/L), exceeding the USEPA secondary drinking water standard (50 µg/L). Higher mean Mg/Ca and Ba/Ca ratios (range 2.3-3.4) may indicate different interactions between seawater and groundwater throughout the year. Although metal concentrations were within the limits of the USEPA drinking water standards, emerging contaminants, such as manganese, showed concentrations in excess of recommended limits. These metals may interact with background nutritional status with potential implications for growth and development.
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http://dx.doi.org/10.1080/09603123.2018.1499880 | DOI Listing |
Tissue Eng Regen Med
January 2025
Department of Pediatrics, College of Medicine, Ewha Womans University, Seoul, 07804, South Korea.
Background: Exogenous Cushing's syndrome, which results from prolonged glucocorticoid treatment, is associated with metabolic abnormalities. Previously, we reported the inhibitory effect of tonsil-derived mesenchymal stem cell conditioned medium (T-MSC CM) on glucocorticoid signal transduction. In this study, we investigated the therapeutic efficacy of T-MSCs in a mouse model of exogenous Cushing's syndrome.
View Article and Find Full Text PDFEnviron Geochem Health
January 2025
Environment Research Laboratory, Faculty of Science, Nepal Academy of Science and Technology, Khumaltar, Lalitpur, Nepal.
A comprehensive hydrogeochemical analysis of 156 groundwater samples (106 shallow and 50 deep) was conducted in the Kathmandu Valley, Nepal. This study addresses a significant research gap by focusing on the hydro-geochemical composition and contamination of groundwater in the Kathmandu Valley, an area with limited detailed assessments. The novelty of this work lies in its comprehensive analysis of both shallow and deep groundwater, particularly concerning the high concentration of contaminants like arsenic, microbial pathogens, and ammonium, which are critical for public health.
View Article and Find Full Text PDFUrol Res Pract
January 2025
Department of Pharmacology, Ankara University, Faculty of Pharmacy, Ankara, Türkiye.
Objective: To investigate the effects of testosterone (T) treatment, with or without levothyroxine, the most widely used and least effective medication for managing hypothyroidism, on the functional and histological changes in propylthiouracil (PTU)- induced hypothyroid rat bladders.
Methods: Male rats (n=35) were split into control, hypothyroid, hypothyroid rats treated with levothyroxine (20 µg/kg/day, oral, 2-weeks), hypothyroid rats treated with Sustanon (10 mg/kg,iIM, once/week, 2-weeks), and hypothyroid rats treated with combined treatment groups. Hypothyroidism was induced by PTU (0.
Integr Cancer Ther
January 2025
National Centre for Radiation Research and Technology, Egyptian Atomic Energy Authority, Cairo, Egypt.
Objectives: Hepatocellular carcinoma (HCC) represents the third-most prevalent cancer in humans worldwide. The current study's objective is to search for the potentiality of H. Wendl () leaf extract in a nanoemulsion (NE) form in enhancing radiotherapy against HCC induced in rats using diethylnitrosamine (DEN).
View Article and Find Full Text PDFChem Eng J
July 2024
Program in Environmental and Polymer Engineering, Graduate School of INHA University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Korea.
Microplastics (MPs) have been detected in various environmental matrices, drinking water, and food, and their presence is an ecological and human health concern. Most research on MPs has focused solely on their detection and analysis. However, sample pretreatment methods are critical for accurate MP analysis and must be properly established.
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