Respiratory Failure Due To Plant Poisoning: Nicotiana glauca Graham.

J Emerg Med

Department of Emergency Medicine, Ege University, Izmir, Turkey.

Published: September 2018

AI Article Synopsis

  • Cases of poisoning from Nicotiana glauca, often mistaken for spinach or used as a folk remedy, are rare but serious due to its toxic effects on the nervous system.
  • A 72-year-old woman with breast cancer ate the plant to help her condition, experiencing severe nausea, vomiting, confusion, and respiratory failure, which led to her being intubated.
  • Emergency physicians should be aware that patients with incurable diseases may resort to folk remedies like N. glauca, and symptoms like muscle paralysis and difficulty breathing could indicate poisoning from this plant.

Article Abstract

Background: Cases of human poisoning associated with Nicotiana glauca Graham are quite rare. Patients may consume the plant by mistaking it for spinach or use it as a folk remedy. The toxin stimulates the acetylcholine receptors in the central and autonomic nervous systems. A prompt and appropriate supportive treatment is crucial for survival.

Case Report: A 72-year-old female with a known breast cancer was brought to our emergency department (ED) with complaints of nausea and vomiting. The patient stated that her complaints started 2 h after she had cooked and eaten a plant in the hopes that it would help cure her cancer. On the second hour after arrival, the patient became confused. It was observed that the chest wall movements had decreased and that the patient had difficulty breathing. Due to respiratory failure, orotracheal intubation was performed to secure the airway. A sample of the plant that was eaten was requested from the patient's relatives. According to an Internet search, the plant sample was identified as N. glauca Graham. The patient was diagnosed with N. glauca Graham poisoning. The patient was extubated after 30 h. On 3-month follow-up, the patient was neurologically intact and had no complaints related to poisoning. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Patients with incurable diseases such as cancer tend to try folk remedies and can end up in ED. In patients who present with muscle paralysis and respiratory failure, emergency physicians should consider N. glauca Graham as a cause of plant poisoning.

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Source
http://dx.doi.org/10.1016/j.jemermed.2018.06.039DOI Listing

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