The Singularity of nature.

The feasibility of formulating the Singularity of Nature was enunciated by Einstein's mathematical formula, demonstrating the equivalency of energy and mass (E = mc). Despite that statement of principle, it has proven impossible to achieve this goal scientifically by directly merging biology and physics into one continuum. More recently, it has been realized that biology can be traced to its origins by reducing evolutionary biology to cell-cell signaling, the unicellular state being seen as a continuum from genotype to phenotype. Mechanistically, Self-referential Self-organization founded on The First Principles of Physiology offers a mechanistic explanation for 'how and why' evolution has transpired, fueled by the ambiguity (Torday and Miller, 2017a) caused by the differential between internal and external cellular entropy. The reduction of biology to cellular networks uniquely gains purchase to the roles of Quantum Mechanics, such as The Pauli Exclusion Principle, The Heisenberg Uncertainty Principle, Non-Localization and Coherence with their homologies in cellular-molecular biology. This opportunity to find the common denominator between physics and biology predicts that consciousness is the denoument of this continuum. As 'proof of principle', the classic dogmatic association of terminal addition with evolution is shown to be due to cell-cell signaling, both developmentally and phylogenetically, as a manifestation of the Singularity. These novel insights offer the opportunity to empirically formulate the basis for the Singularity of Nature for the first time.