The precise target location for radiofrequency energy delivery was initially determined through electrophysiological signals and with the help of fluoroscopy. The introduction of the 3D mapping system CARTO® (Biosense Webster Inc., Diamond Bar, CA, USA) in recent years for radiofrequency ablation of arrhythmias has provided new therapeutic options. These improvements have led to reduced procedural and fluoroscopic times. The introduction of new software and technology has also improved clinical outcome and helped to understand the substrate of complex arrhythmias. This article provides an overview of the development of the CARTO® system and presents new features of the system.
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http://dx.doi.org/10.1007/s00399-018-0583-x | DOI Listing |
J Magn Reson Imaging
January 2025
Neuromuscular Research Center, Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Background: Quantitative Susceptibility Mapping (QSM) provides a non-invasive post-processing method to investigate alterations in magnetic susceptibility (χ), reflecting iron content within brain regions implicated in neurodegenerative diseases (NDDs).
Purpose: To investigate alterations in thalamic χ in patients with NDDs using QSM.
Study Type: Systematic review and meta-analysis.
Angew Chem Int Ed Engl
January 2025
East China University of Science and Technology, Insitute of Fine Chemicals, Meilong Road 130, Shanghai, China, 200237, Shanghai, CHINA.
Protein clustering/disassembling is a fundamental process in biomolecular condensates, playing crucial roles in cell fate decision and cellular homeostasis. However, the inherent features of protein clustering, especially for its reversible behavior and subtle microenvironment variation, present significant hurdles in probe chemistry for tracking protein clustering dynamics. Herein, we report a bilateral-tailored chemigenetic probe, in which an "amphiphilic" AIEgen QMSO3Cl is covalently conjugated to a protein tag that is genetically fused to protein-of-interest (POI).
View Article and Find Full Text PDFUltramicroscopy
January 2025
Nanopatterning-Nanoanalysis-Photonic Materials Group, Department of Physics, Paderborn University, Warburgerstr. 100, Paderborn, 33098, Germany. Electronic address:
Electron energy-loss spectroscopy (EELS) performed in a scanning transmission electron microscope (STEM) is susceptible to noise, just like every other measurement. EELS measurements are also affected by signal blurring, related to the energy distribution of the electron beam and the detector point spread function (PSF). Moreover, the signal blurring caused by the detector introduces correlation effects, which smooth the noise.
View Article and Find Full Text PDFActa Physiol (Oxf)
February 2025
Deptrtment of Anesthesiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Aim: Tissue clearance is a rapidly evolving technology that allows for the three-dimensional imaging of intact biological tissues. Preexisting tissue-clearing techniques, such as Passive Clarity Technique (PACT) and Clear Unobstructed Brain Imaging Cocktails and Computational Analysis (CUBIC), clear tissues adequately but have distinct disadvantages, such as taking extensive time to clear tissues and degradation of endogenous tissue fluorescence. We developed a new tissue-clearing technique combining PACT and CUBIC protocols to map the neural lineages expressing the transient receptor potential vanilloid type 1 (TRPV1) receptor.
View Article and Find Full Text PDFMed Sci Monit
January 2025
Department of Physical Education, Pusan National University, Busan, South Korea.
BACKGROUND The VICON Toolkit enables three-dimensional (3D) motion capture for gait analysis. Statistical parametric mapping (SPM) is a voxel-based neuroimaging approach used to identify region-specific effects. This study aimed to apply SPM to analyze the joint angles of the hip, knee, and ankle during gait in 20 post-stroke patients using the VICON motion capture system.
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