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Depression and anxiety in multiple sclerosis. Review of a fatal combination.
J Neural Transm (Vienna)
August 2024
Institute of Clinical Neurobiology, Alberichgasse 5/13, Vienna, A-1150, Austria.
Depression and anxiety are the most frequent neuropsychiatric symptoms of multiple sclerosis (MS), an autoimmune-mediated demyelinating neurodegenerative disease. Their prevalence is 25-65% and 20-54%, respectively, often associated with chronic fatigue and cognitive impairment, but usually not correlated with motor and other deficits, suggesting different pathophysiological mechanisms. Both disorders often arise before MS diagnosis, lead to faster disability and impair the quality of life.
View Article and Find Full Text PDFA Study on the Effect of Executive Control Network Functional Connection on the Therapeutic Efficacy of Repetitive Transcranial Magnetic Stimulation in Alzheimer's Disease.
J Alzheimers Dis
June 2024
Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Background: Alzheimer's disease (AD) is a neurodegenerative disease characterized by brain network dysfunction. Few studies have investigated whether the functional connections between executive control networks (ECN) and other brain regions can predict the therapeutic effect of repetitive transcranial magnetic stimulation (rTMS).
Objective: The purpose of this study is to examine the relationship between the functional connectivity (FC) within ECN networks and the efficacy of rTMS.
Mechanistic account of the left auditory cortex for tone-matching in schizophrenia: A pilot transcranial random noise stimulation (tRNS) sham-controlled study.
Asian J Psychiatr
February 2024
Université Claude Bernard Lyon 1, CNRS, INSERM, Centre de Recherche en Neurosciences de Lyon CRNL U1028 UMR5292, PSYR2, F-69500 Bron, France; Centre Hospitalier Le Vinatier, F-69500 Bron, France. Electronic address:
Objective: Deficits in the ability to match tones following brief delay and their contribution to higher-order cognitive alterations have been repeatedly documented in schizophrenia. The aim was to explore if left fronto-temporal high-frequency transcranial random noise stimulation (hf-tRNS), with electrodes placed over brain regions involved in tone-matching would significantly modulate performances in participants with schizophrenia.
Methods: In a randomized, double-blind sham-controlled study, 10 participants with schizophrenia were allocated to receive ten sessions of either active or sham hf-tRNS.
Tuberculum Sellae Meningioma: Report of Two Cases and Literature Review of Limits of the Transcranial and Endonasal Endoscopic Approaches.
Acta Neurochir Suppl
December 2023
Institute of Neurosurgery, Catholic University of Rome, Rome, Italy.
Article Synopsis
- Tuberculum sellae (TS) meningioma is a common type of brain tumor located at the anterior skull base, and this review discusses various surgical approaches to treat it.
- Two female patients with TS meningioma underwent surgery at Policlinico Gemelli in Rome in October 2021, with different surgical techniques implemented to address their visual issues.
- The study concludes that both transcranial and transsphenoidal surgical approaches are effective for safely removing TS meningiomas while potentially improving patients' visual function, highlighting the importance of understanding the tumor's relationship with surrounding structures.
Quantitative Anatomical Comparison of Surgical Approaches to Meckel's Cave.
J Clin Med
October 2023
Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCSS, 00168 Rome, Italy.
Background: Meckel's cave is a challenging surgical target due to its deep location and proximity to vital neurovascular structures. Surgeons have developed various microsurgical transcranial approaches (MTAs) to access it, but there is no consensus on the best method. Newer endoscopic approaches have also emerged.
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