Objective: To study the feasibility of using two stents (a combination of multilayer stent [MS] and stent graft [SG]) in the treatment of a juxtarenal aortic aneurysm that involves a significant branch artery and to determine the advantages and disadvantages of using SGs upstream and downstream from the aneurysm so as to provide some theoretical guidance for preoperative clinical decision-making in the future.
Methods: Four ideal geometric models were established for numerical computation: case 1 refers to an aneurysm without the use of stents, case 2 represents the implantation of two MSs in an aneurysm, and case 3 (SG + MS) and case 4 (MS + SG) both involve the treatment of an aneurysm by using a combination of SG and MG.
Results: The aneurysm pressure is slightly lower and there are more vortices when the SG is implanted (case 3 and case 4). In particular, for case 4, additional vortices appear in the sac and the area of the low-wall shear stress is larger on the aneurysm compared with those of the other three cases. However, the pressure becomes uneven, and a peak pressure region is observed on the wall of the aneurysm, and therefore, the aneurysmal wall will become buckled. In addition, the flux of the renal artery in the four cases is greater than that in the normal case.
Conclusion: The arrangements in cases 3 and 4 can effectively isolate the aneurysm from circulation, but clinically, it is necessary to avoid such a high-risk situation wherein the SG is positioned downstream of the aneurysm (case 4), even though this leads to improved isolation.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.clinbiomech.2018.07.018 | DOI Listing |
ACS Chem Neurosci
January 2025
Jiangxi Key Laboratory of Neurological Diseases, Department of Neurosurgery, the first Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 17 Yongwaizheng Street, Nanchang, Jiangxi 330006, China.
Patients with spinal cord injury (SCI) may develop depression, which can affect their rehabilitation. However, the underlying mechanism of depression in SCI patients remains unclear. Previous studies have revealed increased p38 MAPK phosphorylation in the rat hippocampus after SCI, accompanied by depression-like behaviors.
View Article and Find Full Text PDFNeurosurg Rev
January 2025
Lab in Biotechnology and Biosignal Transduction, Department of Orthodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-77, Tamil Nadu, India.
Ann Med
December 2025
Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, PR China.
Background: This study aimed to investigate the demographics and to evaluate long-term outcomes of acute type A aortic dissection (ATAAD) in surgically treated patients ≤40 years in China.
Methods: This study included patients aged ≤40 with ATAAD who underwent surgical treatment at our institution between 2015 and 2019. The patients were categorized into groups according to heritable thoracic aortic disease (HTAD) presence or absence.
Neuroradiol J
January 2025
Department of Neurology, Neurosurgery & Radiology, University of Iowa Hospitals and Clinics, USA.
Background: The Woven EndoBridge 17 (WEB-17) is the latest advancement in the WEB device family. Comprehensive data on its occlusion rates, procedural complications, and mortality is lacking. This meta-analysis aimed to evaluate the efficacy and safety of the WEB-17 device in intracranial aneurysms (IAs).
View Article and Find Full Text PDFLife Metab
February 2025
Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Institutes of Biomedical Sciences, Fudan University, Shanghai 200438, China.
Abdominal aortic aneurysm (AAA) is strongly correlated with obesity, partially due to the abnormal expansion of abdominal perivascular adipose tissue (PVAT). Cell death-inducing DNA fragmentation factor-like effector C (CIDEC), also known as fat-specific protein 27 (FSP27) in rodents, is specifically expressed in adipose tissue where it mediates lipid droplet fusion and adipose tissue expansion. Whether and how CIDEC/FSP27 plays a role in AAA pathology remains elusive.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!