Low-Density Lipoprotein Cholesterol and Cardiovascular Risk Reduction: How Low Is Low Enough Without Causing Harm?

JAMA Cardiol

Weill Cornell Medicine, New York, New York.

Published: September 2018

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamacardio.2018.2273DOI Listing

Publication Analysis

Top Keywords

low-density lipoprotein
4
lipoprotein cholesterol
4
cholesterol cardiovascular
4
cardiovascular risk
4
risk reduction
4
reduction low
4
low low
4
low causing
4
causing harm?
4
low
2

Similar Publications

Background: The rising incidence of kidney stones underscores the imperative to devise effective preventive measures. While a robust association between cardiovascular disease (CVD) and kidney stones exists, the current research landscape lacks investigations between cardiovascular health (CVH) and kidney stones. This study aims to explore the association between CVH, assessed by Life's Essential 8 (LE8), and kidney stones, with the role of blood lipids and insulin resistance in this relationship.

View Article and Find Full Text PDF

Age-specific and sex-specific associations of visceral adipose tissue with metabolic health status and cardiovascular disease risk.

Acta Diabetol

January 2025

Division of Life Sciences and Medicine, Department of Endocrinology, The First Affiliated Hospital of USTC, University of Science and Technology of China, Hefei, 230001, China.

Background: Visceral adipose tissue (VAT) is known to play a role in the development of metabolic and cardiovascular disease (CVD). However, the age- and sex-specific associations between VAT and these diseases remain unclear.

Methods: In this cross-sectional study, 1,150 participants (39.

View Article and Find Full Text PDF

Background: While several studies have suggested a connection between Metabolic Syndrome (MetS) and Hidradenitis Suppurativa (HS), a definitive analysis confirming the association between lipid abnormalities and HS based on actual lipid values is lacking. Previous research, using odds ratios from ICD codes, indicates links between elevated triglycerides and low high-density lipoprotein levels with HS. However, these findings may not fully represent real-life situations, as no comprehensive analysis using actual lipid measurements has been performed.

View Article and Find Full Text PDF

Metabolic indices significantly impact cardiovascular health. Research on the influence of metabolic indices on resting pulse rate in younger adults is needed. Utilizing the National Longitudinal Study of Adolescent to Adult Health (Add Health) Wave 5 Public-use biological data, we performed a multiple linear regression analysis to determine the predictive factors of resting pulse rate in adults aged 32-42 years.

View Article and Find Full Text PDF

Dyslipidemia, a significant risk factor for cardiovascular disease (CVD), is marked by abnormal lipid levels, such as the elevated lowering of low-density lipoprotein cholesterol (LDL-C). Statins are the first-line treatment for LDL-C reduction. Pitavastatin (PIT) has shown potential in lowering LDL-C and improving high-density lipoprotein cholesterol (HDL-C).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!