PATRIOT is a phase I study of the ATR inhibitor, AZD6738, as monotherapy, and in combination with palliative radiotherapy. Here, we describe the protocol for this study, which opened in 2014 and is currently recruiting and comprises dose escalation of both drug and radiotherapy, and expansion cohorts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068075PMC
http://dx.doi.org/10.1016/j.ctro.2018.06.001DOI Listing

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