Idiopathic, Infectious and Reactive Lesions of the Ear and Temporal Bone.

Head Neck Pathol

Department of Pathology and Lab Medicine, Emory University, 550 Peachtree St. NE, Atlanta, GA, 30308, USA.

Published: September 2018

A number of infectious, inflammatory and idiopathic lesions develop within otologic tissues that may share similar clinical and/or microscopic features. This review first provides a working classification for otitis externa, and then otitis media and includes two recently described entities, eosinophilic otitis media and otitis media with ANCA-associated vasculitis. Next, the microscopic findings of a spectrum of otopathologic conditions are described, including post-inflammatory conditions such as tympanosclerosis and aural polyps, an overview of animate aural foreign body as well as iatrogenic aural foreign body reactions. Finally, a review of fungal disease affecting the ear with a brief synopsis of Candida auris, a recently described and virulent organism, is presented.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081288PMC
http://dx.doi.org/10.1007/s12105-018-0952-0DOI Listing

Publication Analysis

Top Keywords

otitis media
12
aural foreign
8
foreign body
8
idiopathic infectious
4
infectious reactive
4
reactive lesions
4
lesions ear
4
ear temporal
4
temporal bone
4
bone number
4

Similar Publications

Introduction: Environmental changes and modifications in leisure habits have facilitated the emergence of new bacteria responsible for causing ear infections with different presentations. In this context, Turicella otitidis is a pathogen for which isolated cases of external and middle ear infections have been reported. However, our experience indicates a resurgence in its occurrence in recent years.

View Article and Find Full Text PDF

Unlabelled: This paper presents the results of the evaluation of cellular and humoral immunity in chronic purulent otitis media (CPOM), as well as cytokine status, and studies the effect of azoximers bromide on the immunity system in CPOM.

Objective: To study the clinical and immunologic effectiveness of azoximer bromide in the postoperative period during tympanoplasty in CPOM patients.

Material And Methods: Forty-nine patients with mesotympanitis and epitympanitis were examined.

View Article and Find Full Text PDF

Objective: This study aimed to assess the functional and clinical outcomes of endoscopic Type 1 tympanoplasty in patients with chronic otitis media and tympanic membrane perforations, focusing on hearing improvement and graft success rates.

Methods: This retrospective study included 46 patients with dry tympanic membrane perforations who underwent endoscopic Type 1 tympanoplasty. Audiometric data, including pure tone averages (PTA) and air-bone gap (ABG) measurements at four frequencies (500, 1000, 2000, and 4000 Hz), were collected preoperatively and postoperatively.

View Article and Find Full Text PDF

TMCO1-deficient mice exhibit a high incidence of otitis media associated with impaired bone homeostasis in the middle ear.

Am J Pathol

December 2024

Hearing and Speech Rehabilitation Institute, College of Special Education and Rehabilitation, Binzhou Medical University, Yantai, China. Electronic address:

Craniofacial dysmorphism, skeletal anomalies and impaired intellectual development syndrome" (CFSMR1; OMIM#213980) is characterized by craniofacial dysmorphism, skeletal anomalies, and mental retardation. However, reports of hearing issues have been limited. To investigate hearing-related aspects of CFSMR1, Tmco1 knockout mice (Tmco1) exhibiting similar symptoms to human patients were utilized in this study.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!