Swyer-James-MacLeod syndrome is a rare pulmonary disorder that exhibits unilateral hyperlucency of a part of or the entire lung and because it is usually asimptomatic the diagnostic of this illness is discovered accidentally after a chest X-ray. Although the cause of this disorder is not completely understood, most authors believe that this is due to late sequela of infectious bronchiolitis that occurs during childhood. The symptoms presented by the individuals are often scarce at the moment of diagnostic, but a history of recurrent episodes of pulmonary infection accompanied by dyspnea, hemoptysis and/or chronic productive cough should raise the suspicion for such a diagnosis. Swyer-James-MacLeod syndrome can be interpreted as asthma or pulmonary embolism and this can result in inappropriate therapy. This case report describes a 38-year-old patient with chronic respiratory symptoms diagnosed on the findings of the chest X-ray and high resolution CT.
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http://dx.doi.org/10.26574/maedica.2018.13.2.143 | DOI Listing |
Commun Med (Lond)
January 2025
Division of Pulmonary Medicine, Department of Medicine, Lausanne University Hospital (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland.
Background: Bronchiolitis Obliterans Syndrome (BOS), a fibrotic airway disease that may develop after lung transplantation, conventionally relies on pulmonary function tests (PFTs) for diagnosis due to limitations of CT imaging. Deep neural networks (DNNs) have not previously been used for BOS detection. This study aims to train a DNN to detect BOS in CT scans using an approach tailored for low-data scenarios.
View Article and Find Full Text PDFRespir Res
December 2024
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Background: The composite physiologic index (CPI) was developed to estimate the extent of interstitial lung disease (ILD) in idiopathic pulmonary fibrosis (IPF) patients based on pulmonary function tests (PFTs). The CALIPER-revised version of the CPI (CALIPER-CPI) was also developed to estimate the volume fraction of ILD measured by CALIPER, an automated quantitative CT postprocessing software. Recently, artificial intelligence-based quantitative CT image analysis software (AIQCT), which can be used to quantify the bronchial volume separately from the ILD volume, was developed and validated in IPF.
View Article and Find Full Text PDFCureus
September 2024
Pulmonology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Swyer-James-MacLeod syndrome (SJMS) also known as hyperlucent lung syndrome is a condition that occurs as a complication of infectious bronchiolitis obliterans. It is characterized by inflammation and fibrosis of the affected area of the lung resulting in ventilation and perfusion mismatch ultimately leading to underdevelopment of the affected lung. A key feature used for diagnosis is unilateral small lung with hyperlucency on a chest radiograph.
View Article and Find Full Text PDFCureus
September 2024
Epidemiology, Womack Army Medical Center, Fayetteville, USA.
J Nucl Med Technol
September 2024
Department of Radiology, Mayo Clinic, Scottsdale, Arizona; and
We present a rare finding on lung ventilation-perfusion (V/Q) scintigraphy for a woman with longstanding dyspnea. CT of the chest showed volume loss on the right side, which raised concern about possible bronchiolitis obliterans or Swyer-James-MacLeod syndrome; however, the right pulmonary artery could not be visualized. A subsequent V/Q scan showed absence of perfusion and decreased ventilation to the entire right lung, consistent with agenesis of the right pulmonary artery.
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