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Porokeratosis is a group of chronic dermatoses characterized by the presence of cornoid lamellae. Disseminated superficial actinic porokeratosis (DSAP) is a common subtype, presenting as multiple small annular scaly lesions primarily in sun-exposed areas. While previous studies have documented DSAP in prostate cancer patients, the association with androgen deprivation therapy (ADT) has not been reported.

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  • Majocchi's granuloma is a dermatological condition where dermatophytes invade deeper skin layers, often triggered by trauma or excessive use of topical corticosteroids.
  • A 57-year-old man experienced itchy skin lesions on his right ankle after using over-the-counter steroids, leading to the diagnosis of Majocchi's granuloma evidenced by clinical and histopathological findings.
  • The patient was treated with oral terbinafine and topical luliconazole, resulting in resolution of lesions within three weeks, though he was advised to continue treatment for two months.
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  • A two-year-old girl experienced misdiagnoses such as tinea corporis and psoriasis, leading to ineffective treatments until a proper evaluation revealed her low zinc levels.
  • After being diagnosed with AE, she was treated with zinc sulfate, resulting in the complete resolution of her skin lesions within two weeks.
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  • Terbinafine can lead to a skin condition called subacute cutaneous lupus erythematosus (SCLE), prompting a study of 37 affected patients over 26 years.
  • The average patient was 49.5 years old, with symptoms typically appearing 5 weeks after starting terbinafine, primarily presenting as various types of erythematous skin lesions.
  • SCLE was found to resolve within 35 days of stopping the medication and receiving treatment, with no recurrences noted in a year of follow-up, highlighting the importance of prompt diagnosis and management.
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Atypical Manifestations of Syphilis: A 10-Year Retrospective Study.

J Clin Med

March 2024

Section of Dermatology, Department of Health Sciences, University of Genoa, IRCCS-Ospedale Policlinico San Martino, 16132 Genoa, Italy.

: The incidence of syphilis has increased in high-income countries in the past few decades, especially among men who have sex with men. In the present study, we aimed to analyze the correlations between atypical syphilis manifestations and the demographic, clinical, and laboratory features of patients and to review unusual presentations of syphilis reported in the literature. : We conducted a retrospective analysis of 307 patients with syphilis diagnosed between 1 January 2013 and 31 October 2023 at the sexually transmitted infection (STI) centers of the University of Genoa and University of Foggia with both typical and atypical manifestations of disease.

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