Significance: Fundus-guided perimetry is a common clinical tool used to measure visual field sensitivities. Comparisons between perimeters are often made despite relative differences in hardware parameters. We directly compared two perimeters using Weber contrast, which allowed us to assess the clinical gain associated with the extended stimulus range of the macular integrity assessment (MAIA).
Purpose: The purpose of this study was to directly compare sensitivity thresholds for two microperimeters, the MAIA and Optos optical coherence tomography/scanning laser ophthalmoscope, using Weber contrast values. We also examined the clinical utility of the extended stimulus range of the MAIA.
Methods: Six normally sighted adults with no visual field loss and 16 adults with low vision were recruited. Thresholds were measured on the MAIA and Optos using the same threshold algorithm and test points. To compare equivalent units, decibel thresholds were converted to light increments in apostilbs and then to delta increment intensities relative to each instrument's background luminance. Repeatability was assessed for normally sighted adults by testing both instruments on 3 separate days.
Results: For normally sighted observers, mean thresholds were similar on both instruments, and repeatability within microperimeters was high. The MAIA has a 0.3-log lower contrast range and 1.37 higher contrast range. The lower contrast values did not result in lower thresholds for the normally sighted observers on the MAIA. There was a 25% increase in the number of measurable thresholds owing to the higher contrast values in low-vision observers.
Conclusions: The higher contrast range in the MAIA yielded only a small increase in detectable thresholds for participants with visual field loss.
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http://dx.doi.org/10.1097/OPX.0000000000001258 | DOI Listing |
J Vis
January 2025
Department of Psychology, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Beyond the light reflex, the pupil responds to various high-level cognitive processes. Multiple statistical regularities of stimuli have been found to modulate the pupillary response. However, most studies have used auditory or visual temporal sequences as stimuli, and it is unknown whether the pupil size is modulated by statistical regularity in the spatial arrangement of stimuli.
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January 2025
State Key Laboratory of Material Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan, 430074, P. R. China.
Next-generation ionic skin (i-skin) should be self-healing and self-powered, promoting its development toward lightweight, miniaturization, compact, and portable designs. Previously reported self-powered i-skin mostly either lack the ability to self-repair damaged parts or only have self-healing capabilities some components, falling short of achieving complete device self-healability. In this work, a self-bonding strategy is presented to obtain an all-polymerizable deep eutectic solvent (PDES) magnetoelectric i-skin (MIS) that simultaneously achieves self-powering and full-device autonomous self-healability.
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Weill Cornell Medicine, Department of Neurological Surgery, New York, United States.
Significance: Despite the availability of various anti-seizure medications, nearly 1/3 of epilepsy patients experience drug-resistant seizures. These patients are left with invasive surgical options that do not guarantee seizure remission. The development of novel treatment options depends on elucidating the complex biology of seizures and brain networks.
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Beijing Key Laboratory for Bioengineering and Sensing Technology, Daxing Research Institute, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China. Electronic address:
This study focuses on the development and application of tea polyphenol-loaded chitosan/polyaspartic acid nanoparticles (TP@CS/PASP-Nps) embedded within polyvinyl alcohol (PVA) nanofibers to extend the shelf life of fruit. The nanofibers were fabricated using electrospinning, which enhanced the stability and uniform dispersion of the nanoparticles. Experimental results demonstrated that the TP@CS/PASP nanoparticles exhibit significant pH and protease-responsive release of TP, with a cumulative release of 56.
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January 2025
Department of Psychology, Huron University College at Western: London, 1349 Western Road, London, ON, N6G 1H3, Canada.
Previous studies have reported visual motion aftereffects (MAEs) following prolonged exposure to auditory stimuli depicting motion, such as ascending or descending musical scales. The role of attention in modulating these cross-modal MAEs, however, remains unclear. The present study manipulated the level of attention directed to musical scales depicting motion and assessed subsequent changes in MAE strength.
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