Rho GTPases are Ras-family G proteins that regulate many critical cellular functions. Due to their requirement during early embryonic development, investigations into the function of Rho GTPases at a tissue-specific level require inducible and spatially targeted modulation of Rho GTPase activity. Here, we describe the use of ten novel zebrafish transgenics enabling GAL4-specific expression of Rho GTPases to modulate Rho GTPase activity with spatial and temporal control.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891047 | PMC |
| http://dx.doi.org/10.1007/978-1-4939-8612-5_24 | DOI Listing |
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