artemisinin-resistant parasites can be evaluated by examining polymorphisms in the kelch () domain. A total of 69 samples from patients with falciparum malaria were analyzed. All samples were from areas in states in Brazil where the parasite was endemic: Acre ( = 14), Amapá ( = 15), Amazonas ( = 30), and Pará ( = 10). After DNA alignment with the 3D7 reference sequence, all samples were found to be wild type. These data provide a baseline for and reinforce the pertinence of artemisinin combination therapy in Brazilian areas.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6153804 | PMC |
| http://dx.doi.org/10.1128/AAC.00354-18 | DOI Listing |
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