Endometriosis is increasingly recognized as a challenging problem of both diagnosis and management in adolescent gynecology. Areas covered: This special report summarizes the current practices in the evaluation and management of endometriosis in adolescent patients. Expert commentary: We recommend prompt recognition and treatment of endometriosis whenever possible. Management should begin with empiric treatment with NSAIDS and hormonal therapy if complaints of pain interfering with daily activities are elicited. If a patient fails medical therapy after three to six months, surgical intervention is warranted by a clinician experienced in operating in this age range and familiar with the appearance of endometriosis in this age range.
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http://dx.doi.org/10.1080/17446651.2016.1233056 | DOI Listing |
Eur J Obstet Gynecol Reprod Biol
January 2025
Faculty of Medical Sciences of Minas Gerais Belo Horizonte Brazil.
Objective: Endometriosis involves the growth of endometrium-like cells outside the uterus, affecting reproductive-aged women. Symptoms such as dysmenorrhea, pelvic pain, and infertility significantly impair quality of life. Among therapeutic options, progestogens have demonstrated efficacy in managing pain and reducing recurrence rates.
View Article and Find Full Text PDFExpert Opin Pharmacother
January 2025
Obstetrics and Gynecology Department Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
Introduction: Endometriosis is a chronic inflammatory estrogen-dependent disease affecting 10% of women worldwide leading to chronic pelvic pain and infertility which may be treated clinically or surgically.
Areas Covered: Current literaure was reviewed using the keywords 'gonadotropin releasing hormone agonists (GnRHa),' 'endometriosis,' 'infertility' and 'chronic pelvic pain.' Relevant papers prioritizing randomized controlled clinical trials (RCT), systematic reviews, meta-analyses, as well as international guidelines were evaluated.
J Clin Med
January 2025
Department of Gynecology and Obstetrics, University Hospital RWTH Aachen, 52074 Aachen, Germany.
: Endometriosis is a chronic gynecological disorder characterized by ectopic endometrial-like tissue. The symptoms of this disease negatively affect the patient's quality of life, both physically and mentally. This study aims to identify key factors impacting health-related quality of life in endometriosis patients.
View Article and Find Full Text PDFMicroorganisms
January 2025
Clinic of Obstetrics & Gynaecology, University of "Aldo Moro", Cap 70124 Bari, Italy.
Chronic endometritis (CE) is a persistent inflammatory condition of the endometrium characterized by abnormal infiltration of plasma cells into the endometrial stroma. Frequently associated with repeated implantation failure, recurrent pregnancy loss, and infertility, CE significantly impacts women's health, contributing to conditions such as abnormal uterine bleeding and endometriosis. Treatment typically involves antibiotic therapy; however, the efficacy of these treatments is increasingly compromised by the rise of antimicrobial resistance (AMR).
View Article and Find Full Text PDFBiomolecules
January 2025
ENDOLIFE, 28 Rue de Courcelles, 75008 Paris, France.
Endometriosis is a chronic, estrogen-dependent disorder associated with the presence of endometrial cells mainly in the pelvic cavity, causing systemic immune inflammation, infertility, epigenetic dysregulation of differential DNA methylation, coelomic metaplasia, and pain. It affects approximately 10-12% of women. Despite decades of research, full pathophysiology, a diagnostic roadmap, and clinical management strategies for endometriosis are not yet fully elucidated.
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