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Insights into the identification, prevention, and treatment of neurovascular compromise in upper extremity surgery are provided in this chapter, focusing on commonly encountered injuries susceptible to intraoperative or postoperative issues. The authors highlight the importance of knowledge of anatomy, meticulous dissection, and preparation to navigate complex surgical scenarios effectively. Furthermore, proactive approaches to managing difficult situations encountered during surgery are outlined, emphasizing timely recognition and decisive action.
View Article and Find Full Text PDFTEG-Guided Anticoagulation Assessment in Deep Vein Arterialization: A Prospective Analysis.
Ann Vasc Surg
December 2024
Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA. Electronic address:
Introduction: Deep Vein Arterialization (DVA) is an innovative surgical technique aimed at enhancing blood flow in compromised limbs facing amputation. Maintenance of flow post-revascularization is crucial to limb salvage. As this is a new technique, no standardized thromboprophylaxis regime is currently established, and post-procedure thromboprophylaxis is at the discretion of the proceduralist.
View Article and Find Full Text PDF[Use of hydroxychloroquine in recurrent immune-mediated obstetric diseases (excluding systemic lupus): Scientific basis and evidence].
Rev Med Interne
December 2024
Service de médecine interne et inflammation, département inflammation-immunopathologie-biothérapie (DMU I3), CEREMAIAA, hôpital Saint-Antoine, AP-HP, Sorbonne université, Paris, France.
Hydroxychloroquine (HCQ), a synthetic antimalarial, is recognized for its immunomodulatory, anti-inflammatory and vascular-protective effects. In 20-30% of cases of primary obstetrical antiphospholipid syndrome (APS), the combination of antiplatelet aggregation and prophylactic anticoagulation fails to prevent obstetrical complications, a situation referred to as refractory obstetrical APS. This is partly due to the pro-inflammatory effects of antiphospholipid antibodies (aPL) binding to decidual and trophoblastic cells, which compromise embryonic implantation and placentation.
View Article and Find Full Text PDFDecellularization of human iliac artery: A vascular scaffold for peripheral repairs with human mesenchymal cells.
Tissue Cell
December 2024
National Institute of Medical Sciences and Nutrition of Mexico Salvador Zubirán (INCMNSZ), Vasco de Quiroga 15, Belisario Domínguez Secc. 16, Tlalpan, Ciudad de México 14080, Mexico.
This work presents strong evidence supporting the use of decellularized human iliac arteries combined with adipose tissue-derived stem cells (hASCs) as a promising alternative for vascular tissue engineering, opening the path to future treatments for peripheral artery disease (PAD). PAD is a progressive condition with high rates of amputation and mortality due to ischemic damage and limited graft options. Traditional synthetic grafts often fail due to poor integration, while autologous grafts may be unsuitable for patients with compromised vascular health.
View Article and Find Full Text PDFProactive esophageal cooling during radiofrequency cardiac ablation: data update including applications in very high-power short duration ablation.
Expert Rev Med Devices
January 2025
Cardiac Electrophysiology, NorthShore University Health System, Evanston, IL, USA.
Introduction: Proactive esophageal cooling reduces injury during radiofrequency (RF) ablation of the left atrium (LA) for the treatment of atrial fibrillation (AF). New catheters are capable of higher wattage settings up to 90 W (very high-power short duration, vHPSD) for 4 s. Varying power and duration, however, does not eliminate the risk of thermal injury.
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