Genistein is a phytoestrogen found in soy. We previously found that adult exposure to dietary levels of genistein affected gestation time, parturition time, litter size, pup weight, and pup mortality in CD-1 mice. The present study investigated the effects of adult genistein exposure on follicle number and gene expression in the ovaries of CD-1 mice. We found that exposure to genistein had no effect on follicle number, but it did affect the expression of apoptotic regulatory genes (Bax, Bcl-2, Bid, and Dffa) in the ovary.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174104 | PMC |
| http://dx.doi.org/10.1016/j.reprotox.2018.07.085 | DOI Listing |
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