AI Article Synopsis

  • Hypertension is a significant public health issue in low- and middle-income countries, particularly in Guinea, where medicinal plants are commonly used for treatment.
  • A study examined the prevalence of hypertension in Pounthioun and Dowsare districts, revealing a rate of 44.9% among 316 participants, with most being women aged 45-74.
  • Ethnobotanical research identified 15 medicinal plant species used by hypertensive patients, highlighting Hymenocardia acida and Uapaca togoensis as notable for their phytochemical properties linked to traditional hypertension management.

Article Abstract

Ethnopharmacological Relevance: Hypertension is an important public health challenge in low- and middle-income countries, and in many African countries including Guinea medicinal plants are still widely used for its treatment.

Materials And Methods: The objective of this study was to determine the prevalence of hypertension in two Guinean urban districts (Pounthioun and Dowsare), to describe its management and to collect information on traditional herbal remedies. A total of 316 participants entered the study, 28.2% (89/316) men and 71.8% (227/316) women. Of these, 181 were from Dowsare (50 men and 131 women) and 135 from Pounthioun (39 men and 96 women). The mean age of subjects was 40.8 ± 14.0 years (range18 - 88years), while the majority of subjects (63.3% or 200/316) were 45-74 years old.

Results: The overall prevalence of hypertension was 44.9% (142/316): 46.4% (84/181) from Dowsare and 43.0% (58/135) from Pounthioun. Ethnobotanical investigations among hypertensive patients led to the collection of 15 plant species, among which Hymenocardia acida leaves and Uapaca togoensis stem bark were the most cited. Phytochemical investigation of these two plant species led to the isolation and identification of isovitexin and isoorientin from H. acida, and betulinic acid and lupeol from U. togoensis.

Conclusion: The presence of these constituents in Hymenocardia acida leaves and Uapaca togoensis stem bark may at least in part support their traditional use against hypertension in Guinea.

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http://dx.doi.org/10.1016/j.jep.2018.07.028DOI Listing

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Article Synopsis
  • Hypertension is a significant public health issue in low- and middle-income countries, particularly in Guinea, where medicinal plants are commonly used for treatment.
  • A study examined the prevalence of hypertension in Pounthioun and Dowsare districts, revealing a rate of 44.9% among 316 participants, with most being women aged 45-74.
  • Ethnobotanical research identified 15 medicinal plant species used by hypertensive patients, highlighting Hymenocardia acida and Uapaca togoensis as notable for their phytochemical properties linked to traditional hypertension management.
View Article and Find Full Text PDF

In many developing countries traditional medicine constitutes a major part of health care because of its local availability and affordability compared to modern medicine. However, little is known about the specific uses and availability of medicinal plants. In this research an exploratory study was conducted to determine the uses of three medicinal plants in Cameroon, and to examine their relative distribution and abundance in specific habitats.

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