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Electroconvulsive therapy (ECT) and magnetic seizure therapy (MST) are effective in the treatment of medication-resistant depression. Determining the stimulus frequency resulting in the lowest seizure threshold could produce fewer adverse effects by reducing the overall stimulus intensity. To determine the optimal frequency for seizure induction, four male rhesus macaques were titrated with an increasing number of pulses at fixed frequencies ranging from 5 to 240 pulses per second (pps) using ultrabrief-pulse right-unilateral ECT and circular-coil-on-vertex MST.
View Article and Find Full Text PDFPractical Considerations for the rapid titration of VNS.
Epilepsy Behav Rep
March 2025
Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
For patients with drug-resistant epilepsy who are not candidates for epilepsy surgery, Vagus nerve stimulation (VNS) is the most widely available neuromodulation option and has been available in several countries for 30 years. Given its broad availability and extended history on the market, many healthcare providers (HCPs) have developed individualized practice habits regarding the titration and dosing of VNS. This study provides novel evidence to describe the extent to which VNS management differs among providers and discusses recent literature that indicates how unique programming approaches may impact patient outcomes.
View Article and Find Full Text PDFIdentification of Candidate Characteristics that Predicted a Successful Anesthesiology Residency Program Match in 2024: An Anonymous, Prospective Survey.
J Educ Perioper Med
January 2025
Tricia Pendergrast is a Resident Physician in the Department of Anesthesiology at University of Michigan, Ann Arbor, MI. Jed Wolpaw is the Core Residency Program Director in the Department of Anesthesiology and Critical Care Medicine at Johns Hopkins University School of Medicine, Baltimore, MD. Michael P. Hofkamp is the Director of Undergraduate Medical Education in the Department of Anesthesiology at Baylor Scott & White Medical Center-Temple, Temple, TX.
Background: The primary aim of our study was to identify candidate characteristics that predicted a successful outcome for applicants to anesthesiology residency programs in the 2024 Main Residency Match. The secondary aim of our study was to assess the impact of gold and silver signals on the application process.
Methods: The Baylor Scott & White Research Institute institutional review board approved this study.
Focusing Attention to Improve Throwing Skills in Children With Autism Spectrum Disorder: Exploring the Influence of Working Memory.
Occup Ther Int
January 2025
Department of Motor Behavior, Faculty of Physical Education and Sport Sciences, Razi University, Kermanshah, Iran.
This study is aimed at investigating the impact of internal and external attention focus on learning a throwing skill in children with autism, as well as the relationship between working memory and learning rate. Twenty-four children aged 6-8 years with autism were assigned to internal and external attention groups. Participants performed a throwing task while their working memory was assessed using Cornoldi's working memory test.
View Article and Find Full Text PDFLong-Term Outcomes of a Health Information System-Based Feedback Intervention Study of Antimicrobial Prescriptions in Primary Care Institutions: Follow-Up of a Randomized Cross-Over Controlled Trial.
Infect Drug Resist
January 2025
School of Medicine and Health Management, Guizhou Medical University, Guiyang, Guizhou Province, People's Republic of China.
Purpose: To evaluate the long-term impacts of the feedback intervention on controlling inappropriate use of antimicrobial prescriptions in primary care institutions in China, as a continuation of the previous feedback intervention trial.
Methods: After the intervention ended, we conducted a 12-month follow-up study. The prescription data were collected from the baseline until the end of the follow-up period.
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