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Two hexokinases of the shrimp Penaeus (Litopenaeus) vannamei are differentially expressed during oxygen limited conditions.
Comp Biochem Physiol A Mol Integr Physiol
July 2024
Centro de Investigación en Alimentación y Desarrollo (CIAD), A.C. Carretera Gustavo Enrique Astiazarán Rosas No. 46, Hermosillo, Sonora 83304, Mexico. Electronic address:
The white shrimp Penaeus (Litopenaeus) vannamei is the most cultivated shrimp worldwide. Compared to other shrimp species, it has higher resistance to adverse conditions. During hypoxia, the shrimp reduces oxygen consumption and adjusts energy metabolism via anaerobic glycolysis, among other strategies.
View Article and Find Full Text PDF[Effect of tibial slope on functional recovery in patients undergoing anterior cruciate ligament reconstruction].
Acta Ortop Mex
December 2022
Departamento de Investigación, Instituto de Seguridad y Servicios Sociales para los Trabajadores del Estado (ISSSTE). México.
Introduction: the tibial slope has been identified as one of the factors associated with graft failure after anterior cruciate ligament (ACL) reconstruction; however, its relationship with functional results has been little studied. The main purpose of this study is to determine the effect of the tibial slope on functional recovery in patients undergoing reconstruction of the anterior cruciate ligament.
Material And Methods: we included patients with a diagnosis of anterior cruciate ligament injury undergoing primary reconstruction, from May 2018 to May 2019, who had a complete radiographic and clinical record; also, the scores from questionnaires of the International Knee Documentation Committee (IKDC) and Lysholm scores were collected pre surgical procedures and throughout the one-year follow-up.
Analysis of the MCTP Amino Acid Sequence Reveals the Conservation of Putative Calcium- and Lipid-Binding Pockets Within the C2 Domains In Silico.
J Mol Evol
August 2022
Department of Biomedical and Clinical Sciences (BKV), Linköping University, 581 83, Linköping, Sweden.
Article Synopsis
- MCTPs (Multiple C2 Domains and Transmembrane region Proteins) are related to other important proteins involved in processes like exocytosis and membrane trafficking, but their specific functions have not been thoroughly researched.
- They are found in endosomes and the endoplasmic reticulum, featuring three conserved C2 domains and two transmembrane regions across different species.
- Structural modeling and docking analysis of MCTP's C2 domains in C. elegans suggests they have calcium- and lipid-binding abilities, indicating that MCTPs likely play a crucial, calcium-dependent role in membrane function.
Transferrin Binding Protein B and Transferrin Binding Protein A2 Expand the Transferrin Recognition Range of .
J Bacteriol
June 2020
Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
The bacterial bipartite transferrin receptor is an iron acquisition system that several important human and animal pathogens require for survival. It consists of the TonB-dependent transporter transferrin binding protein A (TbpA) and the surface lipoprotein transferrin binding protein B (TbpB). Curiously, the Tbps are only found in host-specific pathogens and are themselves host specific, meaning that they will bind to the transferrin of their host species but not to the transferrins of other animal species.
View Article and Find Full Text PDFMicroRNA-216b suppresses the cell growth of hepatocellular carcinoma by inhibiting Ubiquitin-specific peptidase 28 expression.
Kaohsiung J Med Sci
June 2020
Department of Surgery, Songshan Hospital of Qingdao University, Qingdao, China.
MicroRNA-216b (miR-216b) has been reported to be downregulated in several tumors, its mechanism is still little-studied in hepatocellular carcinoma (HCC). In the present study, we found that miR-216b was downregulated in HCC, but Ubiquitin-specific peptidase 28 (USP28) was upregulated. In addition, Kaplan-Meier-plotter analysis indicated that liver cancer patients with high miR-216b expression had a longer overall survival, but patients with high USP28 had a shorter overall survival.
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