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| http://dx.doi.org/10.1002/rth2.12084 | DOI Listing |
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Influences of patient positioning and general anesthesia on condylar position and surgical accuracy in orthognathic surgery.
Clin Oral Investig
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Department of Oral and Maxillofacial Surgery, Radboud University Medical Center, Geert Grooteplein 10, Nijmegen, 6525, GA, the Netherlands.
Objectives: To assess the effect of patient positioning and general anesthesia on the condylar position in orthognathic surgery.
Materials And Methods: This prospective study included patients undergoing orthognathic surgery between 2019 and 2020. Four weeks prior to surgery (T0) cone-beam computed tomography (CBCT) scans and intra-oral scans (IOS) were acquired in an upright position.
Nanoparticle innovations in targeted cancer therapy: advancements in antibody-drug conjugates.
Naunyn Schmiedebergs Arch Pharmacol
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Department of Biochemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City, 11829, Cairo, Egypt.
Antibody-drug conjugates (ADCs) have emerged as a promising strategy in targeted cancer therapy, enabling the precise delivery of cytotoxic agents to tumor sites while minimizing systemic toxicity. However, traditional ADCs face significant limitations, including restricted drug loading capacity, where an optimal drug-to-antibody ratio (DAR) is crucial; low DARs may lead to insufficient potency, while high DARs can cause rapid clearance and increased toxicity. Additionally, ADCs often suffer from instability in circulation due to the potential for premature release of cytotoxic agents, resulting in off-target effects and reduced therapeutic efficacy.
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Gastro Unit, Copenhagen University Hospital, Hvidovre, Denmark.
Effect of different 3D-printing systems on the flexural strength of provisional fixed dental prostheses: a systematic review and network meta-analysis of in vitro studies.
BMC Oral Health
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Department of Restorative Dentistry, Recep Tayyip Erdoğan University, Rize, Turkey.
Objectives: The aim of this systematic review and network meta-analysis was to compare the flexural strength of provisional fixed dental prostheses (PFDPs) fabricated using different 3D printing technologies, including digital light processing (DLP), stereolithography (SLA), liquid crystal display (LCD), selective laser sintering (SLS), Digital Light Synthesis (DLS), and fused deposition modeling (FDM).
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M cells targeted H. pylori antigen SAM-FAdE displayed on bacterium-like particles induce protective immunity.
J Nanobiotechnology
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School of First Clinical Medical, Ningxia Medical University, Yinchuan, 750004, China.
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