We introduce a new method for transforming chemical systems into desired logical operators (e.g. NAND gates) or similar signal-manipulation components. The method is based upon open-loop dynamic regulation, where external conditions such as feed-rate, lighting conditions, etc., are modulated according to a prescribed temporal sequence that is independent of the input to the network. The method is first introduced using a simple didactic model. We then show its application in transforming a well-stirred cubic autocatalytic reaction (often referred to as the Selkov-Gray-Scott model) into a logical NAND gate. We also comment on the applicability of the method to biological and other systems.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073645 | PMC |
| http://dx.doi.org/10.1098/rsif.2018.0169 | DOI Listing |
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