AI Article Synopsis
- Doppler parameters are studied to predict neurological outcomes in neonates, particularly focusing on cranial ultrasound abnormalities in fetuses with intrauterine growth restriction (IUGR).
- A study comparing 83 IUGR fetuses to 75 control fetuses found that IUGR fetuses had a significantly higher incidence of cranial ultrasound abnormalities (66.3%) and neonatal mortality compared to controls.
- Absent or reversed end-diastolic velocity in the umbilical artery and ductus venosus were identified as strong predictors of these abnormalities shortly before birth.
Article Abstract
Background: Doppler parameters have been commonly used for the prediction of neonatal outcomes. However, controversies exist with regard to the value of Doppler parameters in predicting the risk of neurological outcomes among neonates.
Objective: This prospective cohort study attempted to assess the value of Doppler parameters in predict ing cranial ultrasound abnormalities (CUAs) in intrauterine growth restriction (IUGR) among fetuses at 28-34 weeks of gestation.
Methods: This was a prospective cohort study of 83 delivered IUGR fetuses and 75 control fetuses matched for gestational age (GA). The value of mentioned Doppler parameters and GA in predicting the risk of CUAs, including periventricular leukomalacia (PVL), intraventricular hemorrhage (IVH), and basal ganglia lesions (BGLs), was analyzed.
Results: The incidence of CUAs among IUGR fetuses (66.3%) was significantly higher (p < 0.001) than in the control group (40%). The incidence of neonatal mortality among IUGR fetuses was significantly higher (p < 0.001) than in the control group. Absent or reversed end-diastolic velocity (AREDV) in the umbilical artery (UA) and the ductus venosus (DV) after adjustment for GA was associated with increased odds of IVH, PVL, BGLs, and any CUA.
Conclusions: GA at birth and AREDV in the UA and the DV within 1 week before childbirth were reliable predictors of CUAs during the neonatal period.
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| http://dx.doi.org/10.1159/000488904 | DOI Listing |
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