AI Article Synopsis

  • Ruxolitinib is an oral JAK1/2 inhibitor used since 2012 in Europe to treat patients with intermediate or high-risk myelofibrosis.
  • Over the years, doctors have become more skilled in using ruxolitinib, leading to more personalized treatment options and improved safety for patients.
  • A group of Austrian experts has developed a consensus on managing ruxolitinib therapy, aligning their recommendations with international guidelines to enhance patient care.

Article Abstract

The oral Janus associated kinase (JAK1/2) inhibitor ruxolitinib has been available for treatment of patients with intermediate or high-risk myelofibrosis in Europe since 2012. Since its introduction, the expertise of prescribing doctors with respect to ruxolitinib function, efficacy and adverse effects has consistently been augmented, resulting in therapy modalities that are better tailored to individual patients as well as in increased safety of the treatment. The present consensus on ruxolitinib therapy management has been elaborated by Austrian experts in myeloproliferative neoplasms in line with international treatment guidelines. Our recommendations aim to contribute to an improved management of patients with myelofibrosis treated with ruxolitinib.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132876PMC
http://dx.doi.org/10.1007/s00508-018-1365-5DOI Listing

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