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Group B (GBS) is a perinatal pathogen and an emerging cause of disease in adults. Culture-independent GBS detection relies on polymerase chain reaction (PCR) of conserved genes, including . We demonstrate suboptimal sensitivity of the existing PCR strategy and validate an improved method based on consensus sequences from >100 GBS genomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051451 | PMC |
| http://dx.doi.org/10.1093/ofid/ofy164 | DOI Listing |
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