Isolation of a novel strain of Monoraphidium sp. and characterization of its potential for α-linolenic acid and biodiesel production.

Bioresour Technol

Key Laboratory of Microbiology, College of Heilongjiang Province, School of Life Sciences, Heilongjiang University, Harbin, PR China; Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang University, Harbin, PR China. Electronic address:

Published: November 2018

α-Linolenic acid (ALA) is an essential fatty acid which cannot be synthesized de novo in mammals and must be ingested regularly in the diet. In this study, a microalgal strain named HDMA-11 was isolated from Lake Ming, China, and was found to accumulate a high ALA content (39.2% of total lipids). Phylogenetic neighbor-joining analysis indicated that HDMA-11 belongs to the genus Monoraphidium (Selenastraceae, Sphaeropleales) and its 18S ribosomal DNA sequence seemed to be a new molecular record of a Monoraphidium species. The fatty acid profiles, biomass productivity and lipid content of HDMA-11 were also investigated in autotrophic conditions. The high levels of polyunsaturated fatty acids in HDMA-11, especially ALA, make it suitable as a source of nutritional supplementation for human health. Furthermore, HDMA-11 exhibited good properties for biodiesel production, characterized by high lipid content (28.5% of dry weight), moderate biomass productivity (31.5 mg L day) and a promising lipid profile.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biortech.2018.07.081DOI Listing

Publication Analysis

Top Keywords

α-linolenic acid
8
biodiesel production
8
fatty acid
8
biomass productivity
8
lipid content
8
hdma-11
5
isolation novel
4
novel strain
4
strain monoraphidium
4
monoraphidium characterization
4

Similar Publications

Mismatched electron and proton transport rates impede the manifestation of effective performance of the electrocatalytic oxygen evolution reaction (OER), thereby limiting its industrial applications. Inspired by the natural protein cluster in PS-II, different organic-inorganic hybrid electrocatalysts were synthesized via a hydrothermal method. -Toluidine (PT), benzoic acid (BA), and -aminobenzoic acid (PABA) were successfully intercalated into NiFe-LDH.

View Article and Find Full Text PDF

Leishmaniases affect millions of people around the world, caused by Leishmania parasites. Leishmania are transmitted by female sandflies from Phlebotominae subfamily during their blood meals. In mammals, promastigotes are phagocytosed mainly by macrophages, differentiate into amastigotes and multiply.

View Article and Find Full Text PDF

Indole-3-propionic acid (IPA), a metabolite produced by gut microbiota through tryptophan metabolism, has recently been identified as playing a pivotal role in bone metabolism. IPA promotes osteoblast differentiation by upregulating mitochondrial transcription factor A (Tfam), contributing to increased bone density and supporting bone repair. Simultaneously, it inhibits the formation and activity of osteoclasts, reducing bone resorption, possibly through modulation of the nuclear factor-κB (NF-κB) pathway and downregulation of osteoclast-associated factors, thereby maintaining bone structural integrity.

View Article and Find Full Text PDF

Effects of miRNAs in inborn error of metabolism and treatment strategies.

Postgrad Med J

January 2025

Department of Pediatric Metabolic Diseases, University of Health Sciences, Ankara Etlik City Hospital, Ankara 06170, Turkey.

Metabolism is the name given to all of the chemical reactions in the cell involving thousands of proteins, including enzymes, receptors, and transporters. Inborn errors of metabolism (IEM) are caused by defects in the production and breakdown of proteins, fats, and carbohydrates. Micro ribonucleic acids (miRNAs) are short non-coding RNA molecules, ⁓19-25 nucleotides long, hairpin-shaped, produced from DNA.

View Article and Find Full Text PDF

Exploring esophagogastric junction morphology and contractile integral: implications for refractory gastroesophageal reflux disease pathophysiology.

Scand J Gastroenterol

January 2025

Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Xiamen Branch, Xiamen, China.

Background: Evaluate the clinical significance of esophagogastric junction (EGJ) morphology and esophagogastric junction contractile integral (EGJ-CI) in refractory gastroesophageal reflux disease (RGERD) patients.

Methods: From June 2021 to June 2023, 144 RGERD patients underwent comprehensive evaluation, recording symptom scores, demographic data. GERD classification (NERD or RE, A-D) was based on endoscopic findings.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!