High Affinity Neutral Bodipy Fluorophores for Mitochondrial Tracking.

ACS Med Chem Lett

Polymers and Functional Materials Division, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad 500007, India.

Published: July 2018

We report the first high affinity neutral Bodipy fluorophores for selective imaging of mitochondria with notable sensitivity (∼100 nM) and insignificant cytotoxicity even at very high concentration (∼100 μM), when tested against HeLa cells. Further, these fluorophores are chemically robust and require no special conditions for storage.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047038PMC
http://dx.doi.org/10.1021/acsmedchemlett.8b00022DOI Listing

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