[Hormonal regulation of the hemostasis system in patients with ischemic heart disease during emotional stress].

A total of 75 patients were examined, suffering from various forms of coronary heart disease (CHD) in conditions of emotional stress (ES). It was found that, as the blood anticoagulant activity and fibrinolysis are intensified in CHD patients in response to ES, the catecholamone effect on the blood coagulation inhibitors is decreased, the correlation between these parameters remaining high. In some patients decrease of the blood anticoagulant activity and fibrinolysis depression are observed in response to ES; decreased blood catecholamine concentrations were detected in the presence of high hydrocortisonemia, weakened hormonal effects, and emergence of negative correlation between these effects and the hemostatic system anticoagulant parameters, that evidences exhausted capacity of the anticoagulant system to defense activation.