A system with many degrees of freedom can be characterized by a covariance matrix; principal components analysis (PCA) focuses on the eigenvalues of this matrix, hoping to find a lower dimensional description. But when the spectrum is nearly continuous, any distinction between components that we keep and those that we ignore becomes arbitrary; it then is natural to ask what happens as we vary this arbitrary cutoff. We argue that this problem is analogous to the momentum shell renormalization group (RG). Following this analogy, we can define relevant and irrelevant operators, where the role of dimensionality is played by properties of the eigenvalue density. These results also suggest an approach to the analysis of real data. As an example, we study neural activity in the vertebrate retina as it responds to naturalistic movies, and find evidence of behavior controlled by a nontrivial fixed point. Applied to financial data, our analysis separates modes dominated by sampling noise from a smaller but still macroscopic number of modes described by a non-Gaussian distribution.
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http://dx.doi.org/10.1007/s10955-017-1770-6 | DOI Listing |
Cancer
January 2025
Department of Urology, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Background: Adverse pathology (AP) is often used as an intermediate end point for long-term outcomes in men with prostate cancer (PCa) who are active surveillance candidates. The association between a commonly used AP definition and long-term outcomes was tested, which identified definitions more strongly linked to a high risk of metastasis.
Methods: Data were reviewed from the Shared Equal Access Regional Cancer Hospital cohort of men undergoing radical prostatectomy (RP) from 1988 to 2020 at nine Veterans Affairs hospitals.
Clin Transl Oncol
January 2025
Urology Department, Hospital Universitari de Bellvitge, L'Hospitalet del Llobregat, Barcelona, Spain.
Introduction: Diagnosing and managing biochemical recurrence (BCR) of prostate cancer (PCa) following primary radical treatment remain a challenge. Implementing next-generation imaging (NGI) techniques has improved metastases detection. However, access to these techniques is heterogeneous, and controversies surround their use and subsequent treatment decisions.
View Article and Find Full Text PDFEur Radiol
December 2024
Department of Medicine, Surgery, and Dentistry, University of Salerno, Baronissi, Italy.
Objectives: To evaluate the quality of radiomics research in prostate MRI for the evaluation of prostate cancer (PCa) through the assessment of METhodological RadiomICs (METRICS) score, a new scoring tool recently introduced with the goal of fostering further improvement in radiomics and machine learning methodology.
Materials And Methods: A literature search was conducted from July 1st, 2019, to November 30th, 2023, to identify original investigations assessing MRI-based radiomics in the setting of PCa. Seven readers with varying expertise underwent a quality assessment using METRICS.
Transl Anim Sci
December 2024
Department of International Development, School of Agriculture, Policy and Development, University of Reading, Reading RG6 6EU, UK.
The objective of this study was to determine the effects of dietary agro-industrial by-products (AIBP) with different amounts of metabolizable energy (ME) and crude protein (CP) on fermentation (96 h) and gas production (GP) kinetics in vitro, as well as acceptability, animal performance, digestibility, and blood parameters in lambs. The gas production technique (GPT) and fermentation characteristics were used in an in vitro trial. This experiment used diets with ME contents of 6.
View Article and Find Full Text PDFSoc Sci Med
November 2024
School of Public Health, The University of Texas Health Sciences Center at Houston, Houston, TX, USA. Electronic address:
Background: We used a social network approach to identify influential community organizations within integrated public health networks in three regions in Texas, US: Houston/Harris County, Cameron County, and Northeast Texas. The study aimed to understand how network structures influence organizational performance in COVID-19 response.
Methods: In collaboration with community partners in each region, we administered a snowball sampling network data collection.
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