Legends and myths regarding eternal youth exist since Antiquity. Prior to the 19th century those wishing to rejuvenate used baths or blood injections, searching to the Fountain of Youth or calling for an alchemist claiming to have found the Elixir of Youth. In the 19th century, Charles Edouard Brown Séquard (1819-1894), after the discovery of the function of the endocrinal glands and testicular secretions, inject himself with an extract from guinea pigs and dogs. He found himself rejuvenated! In the beginning of the 20th century, several surgeons transplanted human testicles coming from death row prisoners inmates or voluntary donors. The transplantation of monkey testicles by Serge Voronoff (1866-1951) had a important aftermath and more than 300 similar interventions took place. The simple ligation of the vas deferens (vasectomy) was recommended by Eugen Steinach (1866-1944). Sigmund Freud was one of the "beneficiaries". Steinach also advised the irradiation of the ovaries for female rejuvenation. In 1935, Alexis Carrel (1873-1944) and Charles Lindbergh (1902-1974) built a pump to feed and regenerate targeted organs. The discovery of pluripotent stem cells and senolytic molecules are building up new hopes on the matter.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.anplas.2018.04.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Behavioral Cetology in the 19th Century: Thomas Beale, Henry Cheever, Thomas Southwell and Their Role in Awakening a Cetacean Protection Consciousness.
J Hist Behav Sci
January 2025
Department of Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
Although naturalists have devoted attention to cetaceans since Antiquity, it was only in the 19th century that cetology underwent a true explosion. Three key cetological works of this period are The Natural History of the Sperm Whale (1839) by Thomas Beale, The Whaleman's Adventures in the Southern Ocean (1850) by Henry Cheever and The Seals and Whales of the British Seas (1881) by Thomas Southwell. Importantly, these three works did not only represent fundamental compendia of scientific knowledge of cetaceans, but also had a crucial role in awakening a cetacean protection consciousness.
View Article and Find Full Text PDFGeorgios Photeinos and his (1835) published in Ottoman Smyrna.
Pharmazie
December 2024
Department of the History of Pharmacy and Ethics, Erciyes University Faculty of Pharmacy, Kayseri, Turkey.
The , authored by Ottoman pharmacist Georgios Photeinos and published in 1835 in Smyrna (modern-day Izmir, T??rkiye), is a historically significant yet largely overlooked work in 19th-century pharmaceutical literature. At a time when modern pharmaceutical resources in Greek were scarce, Photeinos sought to address this gap by creating a comprehensive pharmacopoeia that extensively drew from the Austrian Pharmacopoeia, as well as French and Latin sources. Although he initiated the project around 1804, political upheavals delayed its completion by more than three decades.
View Article and Find Full Text PDFOrigin of proximal femur fracture classification and their namegivers.
Acta Orthop Belg
December 2024
Due to the high incidence of proximal femoral fractures, classifications of these fractures are often used in daily practice. Most classifications are eponymous terms since they bear the name of the person(s) who developed them. In this study we provide an insight in the origin of the classifications and the background of their name givers.
View Article and Find Full Text PDFThe promises of the Prozac century have fallen short; the number of novel, therapeutically significant medications successfully completing development shrinks every year; and the demand for better treatments constantly grows. Answering these hardships is a renewed optimism concerning the efficacy of controlled psychedelic therapy, a that has seen the resurgence of a familiar concept: intoxication as model psychosis. And yet, little has been made of where this peculiar idea originates.
View Article and Find Full Text PDFAdvances and stagnation in airway surgery: A historical perspective.
Cir Esp (Engl Ed)
January 2025
Thoracic Surgery Department, Hospital Universitari de la Ribera, Alzira, València, Spain.
Airway pathology is a complex and incompletely mastered field. Historically, its management was rudimentary, with tracheostomies performed in ancient Egypt, and progress remained stagnant for millennia. Significant advances began in the late 19 century, followed by notable surgical and anesthetic progress in the mid-20 century.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!